Evidence map›Paper›PMID 23036246›Full record

ReviewPediatric clinics of North America2012

Pharmacotherapy of pediatric HIV infection.

Natella Rakhmanina, B Ryan Phelps

Abstract readReview
In one paragraph

Review in Pediatric clinics of North America, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Natella RakhmaninaDivision of Infectious Diseases, Children's National Medical Center, Washington, DC 20010, USA. nrakhman@cnmc.org
B Ryan Phelps

Funding

Effect of Puberty on the Phamacokinetics of Efavirenz in HIV-infected ChildrenK23HD060452 · NICHD · CHILDREN'S RESEARCH INSTITUTE · PI RAKHMANINA, NATELLA YURIEVNA · 2009 to 2012
$498k
NICHD NIH HHS K23 HD060452
6 · The paper itself

Abstract

The delivery of safe and effective antiretroviral therapy to children and adolescents is crucial to save the lives of millions of children worldwide. The immunologic response to human immunodeficiency infection is closely related to a child's development and creates age-specific parameters for the evaluation of therapeutic response to antiretroviral therapy. Similarly, the development and maturation of organ systems involved in drug absorption, distribution, metabolism, and elimination determines significant changes in the pharmacokinetics of antiretroviral drugs throughout childhood. The authors review the evolution in treatment of pediatric HIV from infancy through adolescence.

Indexed as

AdolescentAnti-Retroviral AgentsChildChild, PreschoolFemaleHIVHIV InfectionsHumansPediatricsPregnancyPregnancy Complications, InfectiousAnti-Retroviral Agents

Identifiers

PMID23036246
PMCPMC3465562

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.