Trial reportTrials2012
Development of a manualized protocol of massage therapy for clinical trials in osteoarthritis.
Trial report in Trials, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00970008 (Exploring Massage Benefits for Arthritis of the Knee), which is not on this map. Cited by 7 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Exploring Massage Benefits for Arthritis of the Knee
Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.
- Global trends and neurobiological frontiers of manual therapy in sleep disorders: integrating bibliometrics with clinical evidence.Frontiers in psychiatry · 2026Pooled it
- Efficacy and Safety of Massage for Osteoarthritis of the Knee: a Randomized Clinical Trial.Journal of general internal medicine · 2019Trial
- Model structure for protocol adherence utilizing a manualized therapeutic massage intervention.Journal of complementary & integrative medicine · 2018Trial
- Massage Therapy and Quality of Life in Osteoarthritis of the Knee: A Qualitative Study.Pain medicine (Malden, Mass.) · 2017Trial
- Whole Systems Research Methods in Health Care: A Scoping Review.Journal of alternative and complementary medicine (New York, N.Y.) · 2019Article
- A Standardized, Evidence-Based Massage Therapy Program for Decentralized Elite Paracyclists: Creating the Model.International journal of therapeutic massage & bodywork · 2015Article
- Perceptions of Massage Therapists Participating in a Randomized Controlled Trial.International journal of therapeutic massage & bodywork · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundClinical trial design of manual therapies may be especially challenging as techniques are often individualized and practitioner-dependent. This paper describes our methods in creating a standardized Swedish massage protocol tailored to subjects with osteoarthritis of the knee while respectful of the individualized nature of massage therapy, as well as implementation of this protocol in two randomized clinical trials.
methodsThe manualization process involved a collaborative process between methodologic and clinical experts, with the explicit goals of creating a reproducible semi-structured protocol for massage therapy, while allowing some latitude for therapists' clinical judgment and maintaining consistency with a prior pilot study.
resultsThe manualized protocol addressed identical specified body regions with distinct 30- and 60-min protocols, using standard Swedish strokes. Each protocol specifies the time allocated to each body region. The manualized 30- and 60-min protocols were implemented in a dual-site 24-week randomized dose-finding trial in patients with osteoarthritis of the knee, and is currently being implemented in a three-site 52-week efficacy trial of manualized Swedish massage therapy. In the dose-finding study, therapists adhered to the protocols and significant treatment effects were demonstrated.
conclusionsThe massage protocol was manualized, using standard techniques, and made flexible for individual practitioner and subject needs. The protocol has been applied in two randomized clinical trials. This manualized Swedish massage protocol has real-world utility and can be readily utilized both in the research and clinical settings.
trial registrationClinicaltrials.gov NCT00970008 (18 August 2009).
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.