Evidence map›Paper›PMID 23035149›Full record

ArticleAmerican journal of epidemiology2012

Low birth weight is associated with higher blood pressure variability from childhood to young adulthood: the Bogalusa Heart Study.

Wei Chen, Sathanur R Srinivasan, Lu Yao, Shengxu Li, Pronabesh Dasmahapatra, Camilo Fernandez, Jihua Xu, Gerald S Berenson

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in American journal of epidemiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00005129 (The Bogalusa Heart Study), which is not on this map. Cited by 36 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 1 pooled it
10.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00005129 active not recruitingnot on this map

The Bogalusa Heart Study

TypeobservationalSponsorTulane UniversityRan1973 to 2029Enrolled11,737ConditionsAtherosclerosis, Cardiovascular Diseases, Heart Diseases, Coronary Disease
3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 1 synthesis or guideline pooled it, 66 citations in OpenAlex.

  1. Pooled it
  2. Characterizing the supragingival microbiome of healthy pregnant women.Frontiers in cellular and infection microbiology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Wei ChenTulane Center for Cardiovascular Health, Department of Epidemiology, Tulane University, New Orleans, Louisiana, USA.
Sathanur R Srinivasan
Lu Yao
Shengxu Li
Pronabesh Dasmahapatra
Camilo Fernandez
Jihua Xu
Gerald S Berenson
Tulane University · US

Funding

EVOLUTION OF CARDIOVASCULAR RISK WITH NORMAL AGINGR01AG016592 · NIA · TULANE UNIVERSITY OF LOUISIANA · PI CHEN, WEI · 2000 to 2015
$11.7M
Childhood Secondhand Smoke and Longitudinal Cardiovascular Risk ProfileR01ES021724 · NIEHS · TULANE UNIVERSITY OF LOUISIANA · PI CHEN, WEI · 2012 to 2014
$1.8M
Genetic Modulation on the Relationship of Low Birth Weight to Metabolic SyndromeR03HD061437 · NICHD · TULANE UNIVERSITY OF LOUISIANA · PI CHEN, WEI · 2010 to 2011
$146k
Birth Weight, Postnatal Growth, Blood Pressure and Subclinical Cardiovascular DisR03HD062783 · NICHD · TULANE UNIVERSITY OF LOUISIANA · PI CHEN, WEI · 2010 to 2011
$146k
NIA NIH HHS AG-16592NIA NIH HHS R01 AG016592NICHD NIH HHS HD-061437NICHD NIH HHS HD-062783NICHD NIH HHS R03 HD061437NICHD NIH HHS R03 HD062783NIEHS NIH HHS ES-021724NIEHS NIH HHS R01 ES021724
6 · The paper itself

Abstract

The association between birth weight and long-term within-individual variability of blood pressure (BP) was examined in a longitudinal cohort of 1,454 adults (939 whites and 515 blacks; adulthood age = 19-50 years) enrolled in the Bogalusa Heart Study in Bogalusa, Louisiana, in 1973-2010. BP variability was depicted as standard deviation, coefficient of variation, and deviation from age-predicted values using 6-15 serial BP measurements from childhood to adulthood over an average of 25.7 years. Birth weight was significantly and negatively associated with adulthood BP levels, long-term BP levels, and rate of change. Importantly, low birth weight was significantly associated with increased BP variability in terms of standard deviation, coefficient of variation, and deviation. As evaluated using the regression coefficients, a 1-kg lower birth weight was associated with increases in systolic BP variability measures (-0.38 mm Hg, P = 0.04 for standard deviation; -0.004 mm Hg, P = 0.01 for coefficient of variation; and -0.16 mm Hg, P = 0.04 for deviation) after adjustment for race, age, sex, mean BP levels, and gestational age; similar trends in the associations were noted for diastolic BP variability measures. In conclusion, these findings suggest that birth weight affects not only BP levels but also the magnitude of within-individual BP fluctuations over time through fetal programming in BP regulation mechanisms.

Indexed as

AdolescentAdultAge FactorsBirth WeightBlood PressureChildChild, PreschoolCross-Sectional StudiesFemaleGestational AgeHumansInfant, Low Birth WeightInfant, NewbornLongitudinal StudiesLouisianaMale

Identifiers

PMID23035149
PMCPMC3530367
OpenAlexW2007874546

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.