Trial reportAmerican journal of epidemiology2012
Reproducibility of blood pressure response to the cold pressor test: the GenSalt Study.
Trial report in American journal of epidemiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 38 citations in OpenAlex.
- Melatonin supplementation reduces nighttime blood pressure but does not affect blood pressure reactivity in normotensive adults on a high-sodium diet.American journal of physiology. Regulatory, integrative and comparative physiology · 2023Trial
- Genome-wide linkage and regional association study of blood pressure response to the cold pressor test in Han Chinese: the genetic epidemiology network of salt sensitivity study.Circulation. Cardiovascular genetics · 2014Trial
- Between-visit reproducibility of cerebrovascular and cardiovascular reactivity during the cold pressor test.American journal of physiology. Heart and circulatory physiology · 2026Article
- A Touch Enabled Hemodynamic and Metabolic Monitor.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- TAME Pain data release: using audio signals to characterize pain.Scientific data · 2025Article
- Pain is Modulated Differently Between Females With and Without Patellofemoral Pain: Factors Related to Sensitization.Journal of athletic training · 2025Article
- Virtual stressors with real impact: what virtual reality-based biobehavioral research can teach us about typical and atypical stress responsivity.Translational psychiatry · 2024Review
- Cardiovascular and Ocular Parameter Alterations in Response to Cold Pressor Test in Young Adults.Diagnostics (Basel, Switzerland) · 2024Article
- A prototype photoplethysmography-based cuffless device shows promising results in tracking changes in blood pressure.Frontiers in medical technology · 2024Article
- The Impact of the Cold Pressor Test on Inter-arm Differences in Blood Pressure.International journal of exercise science · 2023Article
- Cold Pressor Test Influences the Cardio-Ankle Vascular Index in Healthy Overweight Young Adults.Pulse (Basel, Switzerland) · 2021Article
- Enabling Wearable Pulse Transit Time-Based Blood Pressure Estimation for Medically Underserved Areas and Health Equity: Comprehensive Evaluation Study.JMIR mHealth and uHealth · 2021Article
- Comprehensive pregnancy monitoring with a network of wireless, soft, and flexible sensors in high- and low-resource health settings.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Reproducibility of the neurocardiovascular responses to common laboratory-based sympathoexcitatory stimuli in young adults.Journal of applied physiology (Bethesda, Md. : 1985) · 2020Article
- Individual sensitivity of cold pressor, environmental meteorological factors associated with blood pressure and its fluctuation.International journal of biometeorology · 2020Article
- Sodium sensitivity of blood pressure in Chinese populations.Journal of human hypertension · 2020Review
- Effect of cold provocation on vessel density in eyes with primary open angle glaucoma: An optical coherence tomography angiography study.Scientific reports · 2019Article
- SeismoWatch: Wearable Cuffless Blood Pressure Monitoring Using Pulse Transit Time.Proceedings of the ACM on interactive, mobile, wearable and ubiquitous technologies · 2017Article
- Blood Pressure Reactivity to the Cold Pressor Test Predicts Hypertension Among Chinese Adults: The GenSalt Study.American journal of hypertension · 2015Article
- Genome-wide association study identifies 8 novel loci associated with blood pressure responses to interventions in Han Chinese.Circulation. Cardiovascular genetics · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 6 institutions in 3 countries.
Funding
Abstract
An elevated blood pressure (BP) response to the cold pressor test (CPT) is associated with increased risk of hypertension and cardiovascular disease. However, it is still unclear whether BP response to the CPT is a stable and reproducible trait over time. Using the same study protocol, the authors repeated the CPT 4.5 years after initial administration among 568 Han Chinese in rural northern China (2003-2005 and 2008-2009). BP was measured using a standard mercury sphygmomanometer prior to and 0, 1, 2, and 4 minutes after the participants immersed their hand in ice water (3°C-5°C) for 1 minute. Absolute BP levels and BP responses during the CPT in the initial and repeated administrations were highly correlated. For example, the correlation coefficients were 0.67, 0.73, 0.71, and 0.72 for absolute systolic BP levels at 0, 1, 2, and 4 minutes after ice-water immersion (all P 's < 0.0001). The correlation coefficients for systolic BP response were 0.41 at 0 minutes, 0.37 at 1 minute, 0.42 for maximum response, and 0.39 for the area under the curve during CPT (all P 's < 0.0001). These data indicate that BP response to the CPT is a long-term reproducible and stable characteristic in the general population.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.