ReviewJournal of the American Dental Association (1939)2012
Detecting viruses by using salivary diagnostics.
Review in Journal of the American Dental Association (1939), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Saliva as a Candidate for COVID-19 Diagnostic Testing: A Meta-Analysis.Frontiers in medicine · 2020Pooled it
- Development of a multiplexed lateral flow assay for the serologic detection of HPV-associated head and neck cancer.Cancer biomarkers : section A of Disease markers · 2025Article
- Direct detection and identification of viruses in saliva using a SpecID ionization modified mass spectrometer.PloS one · 2025Article
- Comparisons of Whole Saliva and Cell Free Saliva by DIA-Based Proteome Profiling.Proteomics. Clinical applications · 2025Article
- Comparison of "hock-a-loogie" saliva versus nasopharyngeal and oropharyngeal swabs for detecting common respiratory pathogens.Heliyon · 2023Article
- Diagnostic Performance Assessment of Saliva RT-PCR and Nasopharyngeal Antigen for the Detection of SARS-CoV-2 in Peru.Microbiology spectrum · 2022Article
- An Insight Into Detection Pathways/Biosensors of Highly Infectious Coronaviruses.Molecular biotechnology · 2022Review
- Sensitive, smartphone-based SARS-CoV-2 detection from clinical saline gargle samples.PNAS nexus · 2022Article
- Salivary Biomarkers in Periodontitis Patients: A Pilot Study.International journal of dentistry · 2022Article
- Noninvasive Determination of CMV Serostatus From Dried Buccal Swab Samples: Assay Development, Validation, and Application to 1.2 Million Samples.The Journal of infectious diseases · 2021Article
- Dentistry and the COVID-19 Outbreak.International dental journal · 2021Review
- Wuhan to World: The COVID-19 Pandemic.Frontiers in cellular and infection microbiology · 2021Review
- Recent advances in graphene-based nanobiosensors for salivary biomarker detection.Biosensors & bioelectronics · 2021Review
- Herpes Simplex Virus Type-1 Infection: Associations with Inflammation and Cognitive Aging in Relation to Schizophrenia.Current topics in behavioral neurosciences · 2020Review
- HIV screening in the dental setting in New York State.PloS one · 2020Article
- Antibody detection by agglutination-PCR (ADAP) enables early diagnosis of HIV infection by oral fluid analysis.Proceedings of the National Academy of Sciences of the United States of America · 2018Article
- Detection of Zika virus using reverse-transcription LAMP coupled with reverse dot blot analysis in saliva.PloS one · 2018Article
- Detection of AMA-M2 in human saliva: Potentials in diagnosis and monitoring of primary biliary cholangitis.Scientific reports · 2017Article
- Quantitative Lateral Flow Assays for Salivary Biomarker Assessment: A Review.Frontiers in public health · 2017Review
- Construction and characterization of the Korean whole saliva proteome to determine ethnic differences in human saliva proteome.PloS one · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
backgroundDiagnostics that involve the use of oral fluids have become increasingly available commercially in recent years and are of particular interest because of their relative ease of use, low cost and noninvasive collection of oral fluid for testing. TYPES OF STUDIES REVIEWED: The authors discuss the use of salivary diagnostics for virus detection with an emphasis on rapid detection of infection by using point-of-care devices. In particular, they review salivary diagnostics for human immunodeficiency virus, hepatitis C virus and human papillomavirus. Oral mucosal transudate contains secretory immunoglobulin (Ig) A, as well as IgM and IgG, which makes it a good source for immunodiagnostic-based devices. CLINICAL IMPLICATIONS: Because patients often visit a dentist more regularly than they do a physician, there is increased discussion in the dental community regarding the need for practitioners to be aware of salivary diagnostics and to be willing and able to administer these tests to their patients.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.