Trial reportThe British journal of surgery2012
Final follow-up of the Multicentre Aneurysm Screening Study (MASS) randomized trial of abdominal aortic aneurysm screening.
Trial report in The British journal of surgery, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02306304 (Ultra-sound for AAA Screening in Smoking Israeli Arab Men), which is not on this map. Cited by 76 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Ultra-sound for AAA Screening in Smoking Israeli Arab Men
Who cites it
76 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Risk factor-targeted abdominal aortic aneurysm screening: systematic review of risk prediction for abdominal aortic aneurysm.The British journal of surgery · 2024Pooled it
- Pooled it
- Risk Factors for Abdominal Aortic Aneurysm in Population-Based Studies: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2018Pooled it
- Recommendations on screening for abdominal aortic aneurysm in primary care.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2017Guideline
- Effects of Nurse-Led Multifactorial Care to Prevent Disability in Community-Living Older People: Cluster Randomized Trial.PloS one · 2016Trial
- Contrast-enhanced Ultrasound in Detecting Endoleaks with Failed Computed Tomography Angiography Diagnosis after Endovascular Abdominal Aortic Aneurysm Repair.Chinese medical journal · 2015Trial
- Targeted abdominal aortic aneurysm screening: a retrospective review of a high-volume Irish tertiary vascular centre.Irish journal of medical science · 2026Article
- Right sided testicular pain as the sole presenting symptom of an abdominal aortic aneurysm: A case report.International journal of surgery case reports · 2025Article
- EVAR Trends over the Past Decade and Their Impact on Aneurysm Mortality: National Health Insurance Data Analysis.Journal of clinical medicine · 2025Article
- Long-term outcomes of abdominal aortic aneurysm screening in patients undergoing transthoracic echocardiography.Journal of medical ultrasonics (2001) · 2025Article
- In-silico trials of targeted screening for abdominal aortic aneurysms using linked healthcare data: A study protocol.PloS one · 2025Article
- Observational
- Prospective clinical evaluation of deep learning for ultrasonographic screening of abdominal aortic aneurysms.NPJ digital medicine · 2024Review
- Disparities in mortality rates from aortic aneurysm and dissection by country-level income status and sex.JTCVS open · 2024Article
- Will DANCAVAS be the most important screening trial in the last 50 years?American journal of preventive cardiology · 2024Article
- Opportunistic Ultrasound Screening for Abdominal Aortic Aneurysm.Annals of vascular diseases · 2024Article
- One-time screening for abdominal aortic aneurysm in Ontario, Canada: a model-based cost-utility analysis.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2024Article
- Prevalence of abdominal aortic aneurysm (AAA) in first-degree relatives: detecting AAA in adult offspring of AAA patients.BJS open · 2024Article
- Association between the non-HDL-cholesterol to HDL- cholesterol ratio and abdominal aortic aneurysm from a Chinese screening program.Lipids in health and disease · 2023Article
- The impact of large proximal aortic neck on endovascular aneurysm repair outcomes.Turk gogus kalp damar cerrahisi dergisi · 2023Article
16 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
backgroundThe long-term effects of abdominal aortic aneurysm (AAA) screening were investigated in extended follow-up from the UK Multicentre Aneurysm Screening Study (MASS) randomized trial.
methodsA population-based sample of men aged 65-74 years were randomized individually to invitation to ultrasound screening (invited group) or to a control group not offered screening. Patients with an AAA (3·0 cm or larger) detected at screening underwent surveillance and were offered surgery after predefined criteria had been met. Cause-specific mortality data were analysed using Cox regression.
resultsSome 67 770 men were enrolled in the study. Over 13 years, there were 224 AAA-related deaths in the invited group and 381 in the control group, a 42 (95 per cent confidence interval 31 to 51) per cent reduction. There was no evidence of effect on other causes of death, but there was an overall reduction in all-cause mortality of 3 (1 to 5) per cent. The degree of benefit seen in earlier years of follow-up was slightly diminished by the occurrence of AAA ruptures in those with an aorta originally screened normal. About half of these ruptures had a baseline aortic diameter in the range 2·5-2·9 cm. It was estimated that 216 men need to be invited to screening to save one death over the next 13 years.
conclusionScreening resulted in a reduction in all-cause mortality, and the benefit in AAA-related mortality continued to accumulate throughout follow-up. REGISTRATION NUMBER: ISRCTN37381646 (http://www.controlled-trials.com).
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.