ArticleGenome biology2012
EpiExplorer: live exploration and global analysis of large epigenomic datasets.
Article in Genome biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
50 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Identification of genetic effects underlying type 2 diabetes in South Asian and European populations.Communications biology · 2022Pooled it
- KnowYourCG: Facilitating base-level sparse methylome interpretation.Science advances · 2025Article
- Spatial Video and EpiExplorer: A Field Strategy to Contextualize Enteric Disease Risk in Slum Environments.International journal of environmental research and public health · 2022Article
- Challenges in Analyzing Functional Epigenetic Data in Perspective of Adolescent Psychiatric Health.International journal of molecular sciences · 2022Review
- A dominant-negative SOX18 mutant disrupts multiple regulatory layers essential to transcription factor activity.Nucleic acids research · 2021Article
- Ten Years of EWAS.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021Review
- Genome-wide investigation of the dynamic changes of epigenome modifications after global DNA methylation editing.Nucleic acids research · 2021Article
- Recommendations for the FAIRification of genomic track metadata.F1000Research · 2021Article
- Article
- Alterations in promoter interaction landscape and transcriptional network underlying metabolic adaptation to diet.Nature communications · 2020Article
- BioMethyl: an R package for biological interpretation of DNA methylation data.Bioinformatics (Oxford, England) · 2019Article
- Colocalization analyses of genomic elements: approaches, recommendations and challenges.Bioinformatics (Oxford, England) · 2019Article
- Homodimerization regulates an endothelial specific signature of the SOX18 transcription factor.Nucleic acids research · 2018Article
- A systems biology network analysis of nutri(epi)genomic changes in endothelial cells exposed to epicatechin metabolites.Scientific reports · 2018Article
- Enrichment analysis with EpiAnnotator.Bioinformatics (Oxford, England) · 2018Article
- Obligatory and facilitative allelic variation in the DNA methylome within common disease-associated loci.Nature communications · 2018Article
- H3K14ac is linked to methylation of H3K9 by the triple Tudor domain of SETDB1.Nature communications · 2017Article
- Application of dual reading domains as novel reagents in chromatin biology reveals a new H3K9me3 and H3K36me2/3 bivalent chromatin state.Epigenetics & chromatin · 2017Article
- Identification of differentially methylated BRCA1 and CRISP2 DNA regions as blood surrogate markers for cardiovascular disease.Scientific reports · 2017Article
- GSuite HyperBrowser: integrative analysis of dataset collections across the genome and epigenome.GigaScience · 2017Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Epigenome mapping consortia are generating resources of tremendous value for studying epigenetic regulation. To maximize their utility and impact, new tools are needed that facilitate interactive analysis of epigenome datasets. Here we describe EpiExplorer, a web tool for exploring genome and epigenome data on a genomic scale. We demonstrate EpiExplorer's utility by describing a hypothesis-generating analysis of DNA hydroxymethylation in relation to public reference maps of the human epigenome. All EpiExplorer analyses are performed dynamically within seconds, using an efficient and versatile text indexing scheme that we introduce to bioinformatics. EpiExplorer is available at http://epiexplorer.mpi-inf.mpg.de.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.