ReviewAmerican journal of reproductive immunology (New York, N.Y. : 1989)2013
Immunobiology of genital tract trauma: endocrine regulation of HIV acquisition in women following sexual assault or genital tract mutilation.
Review in American journal of reproductive immunology (New York, N.Y. : 1989), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 36 citations in OpenAlex.
- The impact of intimate partner violence on PrEP adherence among U.S. Cisgender women at risk for HIV.BMC public health · 2024Trial
- Phase 2a Safety, Pharmacokinetics, and Acceptability of Dapivirine Vaginal Rings in US Postmenopausal Women.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2019Trial
- Sociodemographic Characteristics Associated with Lifetime and Recent Traumatic Experiences Among People Living with HIV in Florida.AIDS and behavior · 2026Article
- Associations between mental health indicators and genital immune biomarkers among recent survivors of forced sex: A case-control analysis.Psychoneuroendocrinology · 2026Article
- Forced vaginal sex and genital immune correlates of HIV risk: a prospective study of female sex workers in Kenya.BMJ global health · 2025Article
- Moving toward transdisciplinary approaches to addressing HIV and psychological trauma: Barriers and facilitators to building collaborations.Journal of traumatic stress · 2023Article
- Intertwined epidemics: progress, gaps, and opportunities to address intimate partner violence and HIV among key populations of women.The lancet. HIV · 2022Review
- HIV Pathogenesis in the Human Female Reproductive Tract.Current HIV/AIDS reports · 2021Review
- The Role of Stress and Genital Immunity in Sexual Trauma and HIV Susceptibility Among Adolescent Girls and Adult Women (The THRIVE Study): Protocol for a Longitudinal Case-Control Study.JMIR research protocols · 2020Article
- A Prospective Study of Exposure to Gender-Based Violence and Risk of Sexually Transmitted Infection Acquisition in the Women's Interagency HIV Study, 1995-2018.Journal of women's health (2002) · 2020Article
- Physiological Changes from Violence-Induced Stress and Trauma Enhance HIV Susceptibility Among Women.Current HIV/AIDS reports · 2019Review
- The Dual Role of the Immune Response in Reproductive Organs During Zika Virus Infection.Frontiers in immunology · 2019Review
- Gender-based violence and trauma in marginalized populations of women: Role of biological embedding and toxic stress.Health care for women international · 2018Article
- Challenges in conducting research on sexual violence and HIV and approaches to overcome them.American journal of reproductive immunology (New York, N.Y. : 1989) · 2017Review
- Tenofovir Inhibits Wound Healing of Epithelial Cells and Fibroblasts from the Upper and Lower Human Female Reproductive Tract.Scientific reports · 2017Article
- Friend or Foe: Innate Sensing of HIV in the Female Reproductive Tract.Current HIV/AIDS reports · 2016Review
- Exploring Genitoanal Injury and HIV Risk Among Women: Menstrual Phase, Hormonal Birth Control, and Injury Frequency and Prevalence.Journal of acquired immune deficiency syndromes (1999) · 2016Observational
- Targeting the SAVA (Substance Abuse, Violence, and AIDS) Syndemic Among Women and Girls: A Global Review of Epidemiology and Integrated Interventions.Journal of acquired immune deficiency syndromes (1999) · 2015Review
- Sex hormones regulate tenofovir-diphosphate in female reproductive tract cells in culture.PloS one · 2014Article
- Personalized Biobehavioral HIV Prevention for Women and Adolescent Girls.Global advances in health and medicine · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Studies on HIV acquisition and transmission in women exposed to sexual trauma throughout their life cycle are lacking, but some findings suggest that rates of HIV acquisition through coercive sex are significantly higher than that seen in consensual sex. Sexual trauma can also occur as a result of female genital mutilation, which makes sex extremely painful and can cause increased abrasions, lacerations, and inflammation, which enhances the risk of HIV acquisition. This review presents an overview of the immune system in the human female reproductive tract (FRT) from adolescence, through puberty to pregnancy and menopause. What is clear is that the foundation of information on immune protection in the FRT throughout the life cycle of women is extremely limited and at some stages such as adolescence and menopause are grossly lacking. Against this backdrop, forced or coercive sexual intercourse as well as genital mutilation further complicates our understanding of the biological risk factors that can result in transmission of HIV and other sexually transmitted infections.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.