ArticleDiabetes care2013
Predicting the glycemic response to gastric bypass surgery in patients with type 2 diabetes.
Article in Diabetes care, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 103 papers, 1 of them a synthesis that pooled it.
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Who cites it
103 citing papers in PubMed, 1 synthesis or guideline pooled it, 199 citations in OpenAlex.
- Predictive factors of type 2 diabetes mellitus remission following bariatric surgery: a meta-analysis.Obesity surgery · 2015Pooled it
- Clinical and metabolic features of the randomised controlled Diabetes Remission Clinical Trial (DiRECT) cohort.Diabetologia · 2018Trial
- Trial
- Predictors of short-term diabetes remission after laparoscopic Roux-en-Y gastric bypass.Obesity surgery · 2015Trial
- Laparoscopic sleeve gastrectomy versus single anastomosis (mini-) gastric bypass for the treatment of type 2 diabetes mellitus: 5-year results of a randomized trial and study of incretin effect.Obesity surgery · 2014Trial
- Relationship between remission rate of type 2 diabetes and skeletal muscle after laparoscopic sleeve gastrectomy.Biomedical reports · 2026Article
- Risk Determinants of Type 2 Diabetes Mellitus with Severe Obesity and Prediction Model for Diabetes Remission after Bariatric Metabolic Surgery.Diabetes & metabolism journal · 2026Article
- Type 2 Diabetes Mellitus Remission, Dream or Reality? A Narrative Review of Current Evidence and Integrated Care Strategies.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2025Review
- Remission of type 2 diabetes one year after esophagectomy with gastric conduit reconstruction: A prospective cohort study.World journal of gastrointestinal surgery · 2025Article
- Assessment of postprandial C peptide in obese patients with prediabetes and type 2 diabetes before and after sleeve gastrectomy.Journal of diabetes and metabolic disorders · 2025Article
- Prioritising patients for publicly funded bariatric surgery in Queensland, Australia.International journal of obesity (2005) · 2024Article
- Effect of bariatric surgery on metabolism in diabetes and obesity comorbidity: Insight from recent research.World journal of diabetes · 2024Article
- Article
- Weight-loss Independent Clinical and Metabolic Biomarkers Associated with Type 2 Diabetes Remission Post-bariatric/metabolic Surgery.Obesity surgery · 2023Observational
- A specific gut microbiota signature is associated with an enhanced GLP-1 and GLP-2 secretion and improved metabolic control in patients with type 2 diabetes after metabolic Roux-en-Y gastric bypass.Frontiers in endocrinology · 2023Article
- Effect of Weight Regain on Body Composition and Metabolic Biomarkers After Sleeve Gastrectomy: a Cross-Sectional Study from a Hospital Database.Obesity surgery · 2023Article
- Type 2 diabetes remission after Roux-en-Y gastric bypass (RYGB), sleeve gastrectomy (SG), and one anastomosis gastric bypass (OAGB): results of the longitudinal assessment of bariatric surgery study.BMC endocrine disorders · 2022Article
- The non-linear relationship between muscle mass and BMI calls into question the use of BMI as a major criterion for eligibility for bariatric surgery.Metabolism open · 2022Article
- Preoperative Plasma Aldosterone Predicts Complete Remission of Type 2 Diabetes after Bariatric Surgery.Obesity facts · 2022Article
- Data assimilation on mechanistic models of glucose metabolism predicts glycemic states in adolescents following bariatric surgery.Frontiers in physiology · 2022Article
43 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo find clinically meaningful preoperative predictors of diabetes remission and conversely inadequate glycemic control after gastric bypass surgery. Predicting the improvement in glycemic control in those with type 2 diabetes after bariatric surgery may help in patient selection. RESEARCH DESIGN AND
methodsPreoperative details of 154 ethnic Chinese subjects with type 2 diabetes were examined for their influence on glycemic outcomes at 1 year after gastric bypass. Remission was defined as HbA(1c) ≤6%. Analysis involved binary logistic regression to identify predictors and provide regression equations and receiver operating characteristic curves to determine clinically useful cutoff values.
resultsRemission was achieved in 107 subjects (69.5%) at 12 months. Diabetes duration <4 years, body mass >35 kg/m(2), and fasting C-peptide concentration >2.9 ng/mL provided three independent preoperative predictors and three clinically useful cutoffs. The regression equation classification plot derived from continuous data correctly assigned 84% of participants. A combination of two or three of these predictors allows a sensitivity of 82% and specificity of 87% for remission. Duration of diabetes (with different cutoff points) and C-peptide also predicted those cases in which HbA(1c) ≤7% was not attained. Percentage weight loss after surgery was also predictive of remission and of less satisfactory outcomes.
conclusionsThe glycemic response to gastric bypass is related to BMI, duration of diabetes, fasting C-peptide (influenced by insulin resistance and residual β-cell function), and weight loss. These data support and refine previous findings in non-Asian populations. Specific ethnic and procedural regression equations and cutoff points may vary.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.