ReviewThe Journal of infectious diseases2012
Childhood tuberculosis and malnutrition.
Review in The Journal of infectious diseases, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05364593 (Evaluating Point-of-care Ultrasound to Improve Tuberculosis Diagnosis in Children), which is not on this map. Cited by 73 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Evaluating Point-of-care Ultrasound to Improve Tuberculosis Diagnosis in Children
Who cites it
73 citing papers in PubMed, 4 syntheses or guidelines pooled it, 168 citations in OpenAlex.
- Effects of zinc and vitamin A supplementation on prognostic markers and treatment outcomes of adults with pulmonary tuberculosis: a systematic review and meta-analysis.BMJ global health · 2022Pooled it
- A systematic review of clinical, epidemiological and demographic predictors of tuberculosis in children with pneumonia.Journal of global health · 2022Pooled it
- Screening tests for active pulmonary tuberculosis in children.The Cochrane database of systematic reviews · 2021Pooled it
- The association between vitamin D status and tuberculosis in children: A meta-analysis.Medicine · 2018Pooled it
- HIV matters when diagnosing TB in young children: an ancillary analysis in children enrolled in the INPUT stepped wedge cluster randomized study.BMC infectious diseases · 2023Trial
- Shorter Treatment for Nonsevere Tuberculosis in African and Indian Children.The New England journal of medicine · 2022Trial
- Associations between El Niño-Southern Oscillation (ENSO) and tuberculosis incidence in China: a nationwide study.One health (Amsterdam, Netherlands) · 2026Article
- Tuberculosis prevalence among children with severe acute malnutrition: a systematic review and meta-analysis.medRxiv : the preprint server for health sciences · 2026Article
- Recreational drug inhalation and socioenvironmental determinants of pulmonary infection in patients with HIV: a hospital-based case control study.BMC public health · 2026Article
- Article
- Rapid diagnosis of pulmonary tuberculosis on induced sputum in children in a high burden setting for HIV and malnutrition.PLOS global public health · 2026Article
- Prevalence, incidence, and outcome of tuberculosis among young hospitalised children with acute illness in Sub-Saharan Africa and South East Asia.Journal of global health · 2025Article
- Long-term survival after therapeutic failure during hospitalization for severe acute malnutrition: Lwiro cohort follow-up in the Eastern Democratic Republic of the Congo.BMC nutrition · 2025Article
- Performance of Tongue Swabs for Tuberculosis Diagnosis in Hospitalized Children Under 5 Years of Age.Open forum infectious diseases · 2025Article
- Multicohort assessment of plasma metabolic signatures of tuberculosis disease in children.Research square · 2025Article
- Article
- Article
- Current Epidemiology of Pediatric Tuberculosis.Indian journal of pediatrics · 2024Review
- Feasibility and utility of a combined nasogastric-tube-and-string-test device for bacteriologic confirmation of pulmonary tuberculosis in young children.Diagnostic microbiology and infectious disease · 2024Article
- Development of tuberculosis treatment decision algorithms in children below 5 years hospitalised with severe acute malnutrition in Zambia and Uganda: a prospective diagnostic cohort study.EClinicalMedicine · 2024Article
13 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
Abstract
Despite the burden of both malnutrition and tuberculosis in children worldwide, there are few studies on the mechanisms that underlie this relationship. From available research, it appears that malnutrition is a predictor of tuberculosis disease and is associated with worse outcomes. This is supported through several lines of evidence, including the role of vitamin D receptor genotypes, malnutrition's effects on immune development, respiratory infections among malnourished children, and limited work specifically on pediatric tuberculosis and malnutrition. Nutritional supplementation has yet to suggest significant benefits on the course of tuberculosis in children. There is a critical need for research on childhood tuberculosis, specifically on how nutritional status affects the risk and progression of tuberculosis and whether nutritional supplementation improves clinical outcomes or prevents disease.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.