ArticleMultidisciplinary respiratory medicine2012
Factors associated with health-related quality of life in adults with asthma. A cross-sectional study.
Article in Multidisciplinary respiratory medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 3 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
31 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Validity and Responsiveness of EQ-5D in Asthma: A Systematic Review and Meta-analysis.The patient · 2025Pooled it
- Health-related quality of life in adult patients with asthma according to asthma control and severity: A systematic review and meta-analysis.Frontiers in pharmacology · 2022Pooled it
- A systematic review of psychological, physical health factors, and quality of life in adult asthma.NPJ primary care respiratory medicine · 2019Pooled it
- Piloting co-developed behaviour change interventions to reduce exposure to air pollution and improve self-reported asthma-related health.Journal of exposure science & environmental epidemiology · 2025Trial
- Cognitive Impairment in Asthma: Emerging Evidence, Clinical Consequences, and Future Directions.Journal of clinical medicine · 2026Review
- Age-related differences in patient-reported quality of care among adult German patients with bronchial asthma: a cross-sectional study.NPJ primary care respiratory medicine · 2026Article
- Association between higher morning preference and better health-related quality of life in asthma.The journal of allergy and clinical immunology. Global · 2025Article
- T2-low severe asthma clinical spectrum and impact: The Greek PHOLLOW cross-sectional study.Clinical and translational allergy · 2025Article
- Article
- Effect of biologic therapies on quality of life in severe asthma: Findings from the PRISM study.The World Allergy Organization journal · 2024Article
- Epidemiology of patients with severe asthma in Japan: a nationwide descriptive study.ERJ open research · 2024Article
- The Asthma App as a New Way to Promote Responsible Short-Acting Beta2-Agonist Use in People With Asthma: Results of a Mixed Methods Pilot Study.JMIR human factors · 2024Article
- Article
- Predictors of change in asthma-related quality of life: a longitudinal real-life study in adult asthmatics.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2023Article
- Article
- The ATLAS ASMA Study: Assessing the Impact of Asthma on Patients' Life - The Spanish Patients' Perspective.Journal of asthma and allergy · 2023Article
- Budget Impact Analysis of Single-Inhaler Fluticasone Furoate/Umeclidinium/Vilanterol in Patients with Asthma in the Dubai Academic Healthcare Corporation.ClinicoEconomics and outcomes research : CEOR · 2023Article
- Health-related quality of life as associated with asthma control, psychological status and insomnia.Upsala journal of medical sciences · 2022Article
- Association of quality of life and disease control with cigarette smoking in patients with severe asthma.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2022Article
- An Assessment of Quality of Life in Patients With Asthma Through Physical, Emotional, Social, and Occupational Aspects. A Cross-Sectional Study.Frontiers in public health · 2022Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe measurement of health-related quality of life (HRQoL) is increasingly recognized as an important endpoint, as a reflection of the effects of the disease from a patient perspective. Our aim was to evaluate the factors determining the HRQoL in patients with asthma, according to the EQ-5D questionnaire.
methodsPatients were included using multi-stage sampling, from Primary Care clinics from all the Autonomous Communities in Spain. The patients included were: over 18 years-old, with a confirmed diagnosis of asthma for at least one year, and had visited a Health Centre in the previous 2 years. The characteristics of the asthma disease, the adherence to treatment, the socio-demographic variables, the smoking habits, and the asthma control were collected using a questionnaire. The influence of the different variables included in the study on the EQ-5D was evaluated using multivariate logistic regression analysis.
resultsA total of 2,125 patients were finally included (57.7% females, mean age 48 years). The response rate was 95.4%. Some factors showed a considerable detrimental effect on the HRQoL of asthmatics. Advanced age, lower educational level and poor control of asthma are significantly associated with a worse quality of life in all the dimensions assessed by the EQ-5D scale. The baseline severity of the asthma, and having been admitted to hospital are related to a worse quality of life in 5 of the 6 dimensions analyzed.
conclusionIn our study, we could identify some factors related to quality of life in asthma patients. The most important were advanced age, lower education level, and poor control of the asthma.
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Registered trials
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