Evidence map›Paper›PMID 23031147›Full record

ArticleJournal of clinical hypertension (Greenwich, Conn.)2012

Prevalence and correlates of low medication adherence in apparent treatment-resistant hypertension.

Marguerite R Irvin, Daichi Shimbo, Devin M Mann, Kristi Reynolds, Marie Krousel-Wood, Nita A Limdi, Daniel T Lackland, David A Calhoun, Suzanne Oparil, Paul Muntner

Erratum issuedAbstract read
In one paragraph

Article in Journal of clinical hypertension (Greenwich, Conn.), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Physician-pharmacist collaboration versus usual care for treatment-resistant hypertension.Journal of the American Society of Hypertension : JASH · 2016
    Trial
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Article
  8. Corrigendum.Journal of clinical hypertension (Greenwich, Conn.) · 2018
    Article
  9. Article
  10. Article
  11. Review
  12. Observational
  13. Article
  14. Article
  15. Article
  16. Article
  17. Observational
  18. New Strategy to Control Blood Pressure: Interactive Mobile Phone Support.Journal of clinical hypertension (Greenwich, Conn.) · 2016
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Marguerite R IrvinDepartment of Epidemiology, School of Public Health, University of Alabama at Birmingham, Birmingham, AL 35294-0022, USA. irvinr@uab.edu
Daichi Shimbo
Devin M Mann
Kristi Reynolds
Marie Krousel-Wood
Nita A Limdi
Daniel T Lackland
David A Calhoun
Suzanne Oparil
Paul Muntner

Funding

VCID and Stroke in a Bi-racial National CohortU01NS041588 · NINDS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI CUSHMAN, MARY, HOWARD, GEORGE · 2002 to 2022
$96.0M
NINDS NIH HHS U01 NS041588
6 · The paper itself

Abstract

Low medication adherence may explain part of the high prevalence of apparent treatment-resistant hypertension (aTRH). The authors assessed medication adherence and aTRH among 4026 participants taking ≥ 3 classes of antihypertensive medication in the population-based Reasons for Geographic and Racial Differences in Stroke (REGARDS) trial using the 4-item Morisky Medication Adherence Scale (MMAS). Low adherence was defined as an MMAS score ≥ 2. Overall, 66% of participants taking ≥ 3 classes of antihypertensive medication had aTRH. Perfect adherence on the MMAS was reported by 67.8% and 70.9% of participants with and without aTRH, respectively. Low adherence was present among 8.1% of participants with aTRH and 5.0% of those without aTRH (P<.001). Among those with aTRH, female sex, residence outside the US stroke belt or stroke buckle, physical inactivity, elevated depressive symptoms, and a history of coronary heart disease were associated with low adherence. In the current study, a small percentage of participants with aTRH had low adherence.

Indexed as

Medication AdherenceAgedAge FactorsAntihypertensive AgentsFemaleGeographyHealth Status IndicatorsHumansHypertensionMalePrevalenceRacial GroupsRisk FactorsStatistics as TopicTreatment FailureUnited StatesAntihypertensive Agents

Identifiers

PMID23031147
PMCPMC3464920

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.