Trial reportBMC cancer2012
Exercise and nutrition for head and neck cancer patients: a patient oriented, clinic-supported randomized controlled trial.
Trial report in BMC cancer, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 17 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Exercise and Nutrition for Head and Neck Cancer Patients: A Patient Oriented, Clinic-Supported Randomized Controlled Trial
A Phase II Study Assessing the Efficacy of Prophylaxis Use of Megestrol Acetate Against Cancer-related Critical Body Weight Loss in Patients With Head and Neck Cancer Who Receiving Concurrent Chemoradiotherapy
Who cites it
17 citing papers in PubMed, 5 syntheses or guidelines pooled it, 39 citations in OpenAlex.
- Multimodal interventions for cachexia management.The Cochrane database of systematic reviews · 2025Pooled it
- Dietary advice with or without oral nutritional supplements for disease-related malnutrition in adults.The Cochrane database of systematic reviews · 2021Pooled it
- Exercise for cancer cachexia in adults.The Cochrane database of systematic reviews · 2021Pooled it
- Dietary interventions for adult cancer survivors.The Cochrane database of systematic reviews · 2019Pooled it
- Effectiveness of Exercise-Based Interventions on Molecular Biomarkers in Head and Neck Cancer (HNC) Survivors: A Systematic Review.Integrative cancer therapiesPooled it
- Head and neck cancer survivors' preferences for and evaluations of a post-treatment dietary intervention.Nutrition journal · 2019Trial
- Demographic, lifestyle, and clinical factors associated with muscle function in patients with head and neck cancer: a prospective cohort study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
- Tailoring the Evidence for Exercise Oncology within Breast Cancer Care.Current oncology (Toronto, Ont.) · 2022Review
- Article
- Exercise in People With Cancer: A Spotlight on Energy Regulation and Cachexia.Frontiers in physiology · 2022Review
- Adult Cancer Survivors' Engagement and Interest in Patient-Centered Research.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2020Article
- Meeting Minimum ESPEN Energy Recommendations Is Not Enough to Maintain Muscle Mass in Head and Neck Cancer Patients.Nutrients · 2019Article
- The prevalence and determinants of return to work in head and neck cancer survivors.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2019Article
- Maintaining physical activity during head and neck cancer treatment: Results of a pilot controlled trial.Head & neck · 2016Article
- A Wellness Program for Cancer Survivors and Caregivers: Developing an Integrative Pilot Program with Exercise, Nutrition, and Complementary Medicine.Journal of cancer education : the official journal of the American Association for Cancer Education · 2016Article
- A clinic-supported group exercise program for head and neck cancer survivors: managing cancer and treatment side effects to improve quality of life.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2015Article
- Clinical review of physical activity and functional considerations in head and neck cancer patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2013Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundResearch on physical activity and nutrition interventions aimed at positively impacting symptom management, treatment-related recovery and quality of life has largely excluded head and neck (HN) cancer populations. This translates into a lack of clinical programming available for these patient populations. HN cancer patients deal with severe weight loss, with more than 70% attributed to lean muscle wasting, leading to extended recovery times, decreased quality of life (QoL), and impaired physical functioning. To date, interventions to address body composition issues have focused solely on diet, despite findings that nutritional therapy alone is insufficient to mitigate changes. A combined physical activity and nutrition intervention, that also incorporates important educational components known to positively impact behaviour change, is warranted for this population. Our pilot work suggests that there is large patient demand and clinic support from the health care professionals for a comprehensive program. METHODS/
designTherefore, the purpose of the present study is to examine the impact and timing of a 12-week PA and nutrition intervention (either during or following treatment) for HN cancer patients on body composition, recovery, serum inflammatory markers and quality of life. In addition, we will examine the impact of a 12-week maintenance program, delivered immediately following the intervention, on adherence, patient-reported outcomes (i.e., management of both physical and psychosocial treatment-related symptoms and side-effects), as well as return to work. DISCUSSION: This research will facilitate advancements in patient wellness, survivorship, and autonomy, and carve the path for a physical-activity and wellness-education model that can be implemented in other cancer centers.
trial registrationCurrent Controlled Trials NCT01681654.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.