ArticlePloS one2012
Pair-rule gene orthologues have unexpected maternal roles in the honeybee (Apis mellifera).
Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 37 citations in OpenAlex.
- Evo-devo and the Biodiversity Crisis.Results and problems in cell differentiation · 2026Article
- Why just fly?Fly · 2025Review
- Same rule, different genes:Science advances · 2024Article
- Development of germline progenitors in larval queen honeybee ovaries.Biology open · 2024Article
- Anterior-posterior patterning of segments in Anopheles stephensi offers insights into the transition from sequential to simultaneous segmentation in holometabolous insects.Journal of experimental zoology. Part B, Molecular and developmental evolution · 2023Article
- The Nasonia pair-rule gene regulatory network retains its function over 300 million years of evolution.Development (Cambridge, England) · 2022Article
- Article
- Shifting roles ofDevelopment (Cambridge, England) · 2019Article
- Diverse Factors Affecting Efficiency of RNAi in Honey Bee Viruses.Frontiers in genetics · 2018Article
- Conservation and variation in pair-rule gene expression and function in the intermediate-germ beetleDevelopment (Cambridge, England) · 2017Article
- MicroRNA-34 directly targets pair-rule genes and cytoskeleton component in the honey bee.Scientific reports · 2017Article
- Rearing and Double-stranded RNA-mediated Gene Knockdown in the Hide Beetle, Dermestes maculatus.Journal of visualized experiments : JoVE · 2016Article
- Hox genes, evo-devo, and the case of the ftz gene.Chromosoma · 2016Review
- Transcriptome Analysis of Honeybee (Apis Mellifera) Haploid and Diploid Embryos Reveals Early Zygotic Transcription during Cleavage.PloS one · 2016Article
- Origin and evolution of the enhancer of split complex.BMC genomics · 2015Article
- Article
- Evidence for deep regulatory similarities in early developmental programs across highly diverged insects.Genome biology and evolution · 2014Article
- Article
- Dual mode of embryonic development is highlighted by expression and function of Nasonia pair-rule genes.eLife · 2014Article
- Evolution of the pair rule gene network: Insights from a centipede.Developmental biology · 2013Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pair-rule genes are a class of segmentation genes first identified in Drosophila melanogaster. In Drosophila, these genes act to translate non-periodic information produced by the overlapping patterns of gap gene expression into patterns of gene expression in every other segment. While pair-rule genes are, for the most part, conserved in metazoans, their function in pair-rule patterning is not. Many of these genes do, however, regulate segmentation in arthropods and do so with dual-segment periodicity. Here we examine the expression and function of honeybee orthologues of Drosophila pair-rule genes. Knockdown of the expression of these genes leads to extensive patterning defects, implying that they act in early patterning, as well as segmentation in honeybee embryos. We show that these pair-rule gene orthologues indeed regulate the expression of honeybee maternal and gap genes implying roles in maternal patterning of the honeybee embryo.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.