Evidence map›Paper›PMID 23029113›Full record

ArticlePloS one2012

Discrimination of low-frequency tones employs temporal fine structure.

Tobias Reichenbach, A J Hudspeth

Abstract read
In one paragraph

Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Amplification through local critical behavior in the mammalian cochlea.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Tobias ReichenbachHoward Hughes Medical Institute and Laboratory of Sensory Neuroscience, The Rockefeller University, New York, NY, USA.
A J Hudspeth

Funding

TRANSDUCTION MECHANISM OF HAIR CELLSR01DC000241 · NIDCD · UNIVERSITY OF TEXAS SW MED CTR/DALLAS · PI HUDSPETH, ALBERT JAMES · 1989 to 2011
$4.1M
ELECTROPHYSIOLOGICAL STUDIES OF THE VOMERONASAL SYSTEMF32DC000241 · NIDCD · WORCESTER FOUNDATION FOR BIOMEDICAL RES · PI JANG, TAICHANG · 1996 to 1998
–
NIDCD NIH HHS DC000241NIDCD NIH HHS F32 DC000241NIDCD NIH HHS R01 DC000241
6 · The paper itself

Abstract

An auditory neuron can preserve the temporal fine structure of a low-frequency tone by phase-locking its response to the stimulus. Apart from sound localization, however, much about the role of this temporal information for signal processing in the brain remains unknown. Through psychoacoustic studies we provide direct evidence that humans employ temporal fine structure to discriminate between frequencies. To this end we construct tones that are based on a single frequency but in which, through the concatenation of wavelets, the phase changes randomly every few cycles. We then test the frequency discrimination of these phase-changing tones, of control tones without phase changes, and of short tones that consist of a single wavelet. For carrier frequencies below a few kilohertz we find that phase changes systematically worsen frequency discrimination. No such effect appears for higher carrier frequencies at which temporal information is not available in the central auditory system.

Indexed as

SoundAcoustic StimulationAdultAuditory PerceptionFemaleHumansMalePsychoacousticsSensory Receptor Cells

Identifiers

PMID23029113
PMCPMC3446936

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.