Evidence map›Paper›PMID 23029060›Full record

ArticlePloS one2012

Routine HIV testing in adolescents and young adults presenting to an outpatient clinic in Durban, South Africa.

Lynn Ramirez-Avila, Kristy Nixon, Farzad Noubary, Janet Giddy, Elena Losina, Rochelle P Walensky, Ingrid V Bassett

Abstract read
In one paragraph

Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  17. Clinic-based routine voluntary HIV testing in a refugee settlement in Uganda.Journal of acquired immune deficiency syndromes (1999) · 2014
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lynn Ramirez-AvilaDivision of Infectious Diseases, Children's Hospital Boston, Boston, MA, USA. lynn.ramirez@childrens.harvard.edu
Kristy Nixon
Farzad Noubary
Janet Giddy
Elena Losina
Rochelle P Walensky
Ingrid V Bassett

Funding

The impact of HIV viral diversity and cellular immunity on HIV pathogenesisP30AI060354 · NIAID · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI ROBERT A. PARKER · 2004 to 2026
$94.4M
Optimizing HIV Care in Less Developed CountriesR01AI058736 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI Kenneth Alan Freedberg, Emily Parker Hyle · 2004 to 2026
$21.5M
PROGRAM FOR AIDS CLINICAL RESEARCH TRAINING (PACRT)T32AI007433 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI MARK J SIEDNER · 1992 to 2026
$11.4M
PARTNERS/FENWAY/SHATTUCK CENTER FOR AIDS RESEARCHP30AI042851 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI WALKER, BRUCE D · 2000 to 2003
$5.7M
Optimizing strategies for universal HIV testingR01MH073445 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI WALENSKY, ROCHELLE P. · 2006 to 2010
$3.3M
Linkage & Retention: A Randomized Trial to Optimize HIV/TB Care in South AfricaR01MH090326 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI BASSETT, INGRID VALERIE · 2010 to 2014
$2.9M
Pediatric Infectious Diseases Research TrainingT32HD055148 · NICHD · BOSTON CHILDREN'S HOSPITAL · PI WESSELS, MICHAEL R · 2008 to 2018
$2.7M
The Efficacy and Impact of Routine HIV and TB Testing in Durban, South AfricaK23AI068458 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI BASSETT, INGRID VALERIE · 2006 to 2010
$669k
Optimal Strategies for Management of HIV DiseaseK24AI062476 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI FREEDBERG, KENNETH ALAN · 2004 to 2008
$512k
NIAID NIH HHS K23 AI068458NIAID NIH HHS K24 AI062476NIAID NIH HHS P30 AI042851NIAID NIH HHS P30 AI060354NIAID NIH HHS P30 AI42851NIAID NIH HHS R01 AI058736NIAID NIH HHS T32 AI 007433NIAID NIH HHS T32 AI007433NICHD NIH HHS T32 HD 055148NICHD NIH HHS T32 HD055148NIMH NIH HHS R01 MH073445NIMH NIH HHS R01 MH090326NIMH NIH HHS R01MH090326
6 · The paper itself

Abstract

objectivesAlthough youth (12-24 years) in Sub-Saharan Africa have a high HIV risk, many have poor access to HIV testing services and are unaware of their status. Our objective was to evaluate the proportion of adolescents (12-17 years) and young adults (18-24 years) who underwent HIV testing and the prevalence among those tested in an urban adult outpatient clinic with a routine HIV testing program in Durban, South Africa.

designWe conducted a retrospective cross-sectional analysis of adolescent and young adult outpatient records between February 2008 and December 2009.

methodsWe determined the number of unique outpatient visitors, HIV tests, and positive rapid tests among those tested.

resultsDuring the study period, 956 adolescents registered in the outpatient clinic, of which 527 (55%) were female. Among adolescents, 260/527 (49%, 95% CI 45-54%) females underwent HIV testing compared to 129/429 (30%, 95% CI 26-35%) males (p<0.01). The HIV prevalence among the 389 (41%, 95% CI 38-44%) adolescents who underwent testing was 16% (95% CI 13-20%) and did not vary by gender (p = 0.99). During this period, there were 2,351 young adult registrations, and of these 1,492 (63%) were female. The proportion consenting for HIV testing was similar among females 980/1,492 (66%, 95% CI 63-68%) and males 543/859 (63%, 95% CI 60-66%, p = 0.25). Among the 1,523 (65%, 95% CI 63-67%) young adults who underwent testing, the HIV prevalence was 22% (95% CI 19-24%) in females versus 14% in males (95% CI 11-17%, p<0.01).

conclusionsAlthough the HIV prevalence is high among youth participating in an adult outpatient clinic routine HIV program, the uptake of testing is low, especially among 12-17 year old males. There is an urgent need to offer targeted, age-appropriate routine HIV testing to youth presenting to outpatient clinics in epidemic settings.

Indexed as

Diagnostic Tests, RoutineAdolescentAdultAge FactorsAmbulatory Care FacilitiesChildCross-Sectional StudiesFemaleHIV InfectionsHumansMaleMass ScreeningPrevalenceRetrospective StudiesSouth AfricaYoung Adult

Identifiers

PMID23029060
PMCPMC3447803

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.