ArticlePloS one2012
Mediterranean style diet and 12-year incidence of cardiovascular diseases: the EPIC-NL cohort study.
Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 8 of them syntheses that pooled it.
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Who cites it
53 citing papers in PubMed, 8 syntheses or guidelines pooled it.
- Impact of adherence to the Mediterranean diet on stroke risk.GeroScience · 2025Pooled it
- The role of the Mediterranean diet in reducing the risk of cognitive impairement, dementia, and Alzheimer's disease: a meta-analysis.GeroScience · 2025Pooled it
- Mediterranean Diet for Primary and Secondary Prevention of Cardiovascular Disease and Mortality: An Updated Systematic Review.Nutrients · 2023Pooled it
- Adherence to the Mediterranean diet and risk of stroke and stroke subtypes.European journal of epidemiology · 2019Pooled it
- Mediterranean diet and cardiovascular disease: a systematic review and meta-analysis of observational studies.European journal of nutrition · 2019Pooled it
- Evaluating Mediterranean diet and risk of chronic disease in cohort studies: an umbrella review of meta-analyses.European journal of epidemiology · 2018Pooled it
- Transferability of the Mediterranean Diet to Non-Mediterranean Countries. What Is and What Is Not the Mediterranean Diet.Nutrients · 2017Pooled it
- Mediterranean diet and health status: an updated meta-analysis and a proposal for a literature-based adherence score.Public health nutrition · 2014Pooled it
- A Randomized Trial Comparing the Specific Carbohydrate Diet to a Mediterranean Diet in Adults With Crohn's Disease.Gastroenterology · 2021Trial
- Scoping Review of Dietary Quality Indices: Heterogeneity of Definitions and Health Associations among Adults.Nutrition reviews · 2026Article
- Dietary Therapies in Inflammatory Bowel Disease and Their Effects on Disease Activity and the Gut Microbiome.Nutrients · 2026Review
- Observational
- Association between genetic risk and adherence to the Dietary Approaches to Stop Hypertension diet for developing venous thromboembolism.Research and practice in thrombosis and haemostasis · 2025Article
- Mediterranean Diet reduces ischemic heart disease risk in diabetes patients until reversed by smoking: Evidence from UK Biobank cohort.PloS one · 2025Article
- Exploring Benefits and Barriers of Plant-Based Diets: Health, Environmental Impact, Food Accessibility and Acceptability.Nutrients · 2023Review
- Zebrafish Model Insights into Mediterranean Diet Liquids: Olive Oil and Wine.Antioxidants (Basel, Switzerland) · 2023Review
- Epidemiology and prevention of venous thromboembolism.Nature reviews. Cardiology · 2023Review
- Adherence to Recommended Eating Patterns Is Associated With Lower Risk of Peripheral Arterial Disease: Results From the Women's Health Initiative.Hypertension (Dallas, Tex. : 1979) · 2021Article
- Contrasting Associations of Prudent and Western Dietary Patterns with Risk of Developing Venous Thromboembolism.The American journal of medicine · 2021Article
- Review
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundA recent meta-analysis showed that a Mediterranean style diet may protect against cardiovascular diseases (CVD). Studies on disease-specific associations are limited. We evaluated the Mediterranean Diet Score (MDS) in relation to incidence of total and specific CVDs.
methodsThe EPIC-NL Study is a cohort of 40,011 men and women aged 20-70 years, examined between 1993 and 1997, with 10-15 years of follow-up. Diet was assessed with a validated food frequency questionnaire and the MDS was based on the daily intakes of vegetables, fruits, legumes and nuts, grains, fish, fatty acids, meat, dairy, and alcohol. Cardiovascular morbidity and mortality were ascertained through linkage with national registries. Cox proportional hazards models were used to estimate hazard ratios (HRs) and 95% confidence intervals (CI) adjusted for age, sex, cohort, smoking, physical activity, total energy intake, and educational level.
resultsIn 34,708 participants free of CVD at baseline, 4881 CVD events occurred, and 487 persons died from CVD. A two unit increment in MDS (range 0-9) was inversely associated with fatal CVD (HR: 0.78; 95%CI: 0.69-0.88), total CVD (HR: 0.95 (0.91-0.98)), myocardial infarction (HR: 0.86 (0.79-0.93)), stroke (HR: 0.88 (0.78-1.00)), and pulmonary embolism (HR: 0.74 (0.59-0.92)). The MDS was not related to incident angina pectoris, transient ischemic attack and peripheral arterial disease.
conclusionBetter adherence to a Mediterranean style diet was more strongly associated with fatal CVD than with total CVD. Disease specific associations were strongest for incident myocardial infarction, stroke and pulmonary embolism.
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