ArticlePloS one2012
Overexpression of CONSTANS homologs CO1 and CO2 fails to alter normal reproductive onset and fall bud set in woody perennial poplar.
Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed, 64 citations in OpenAlex.
- Early birds and night owls: natural variation of circadian traits in plants.Journal of experimental botany · 2026Review
- Flowering pathway genes: key targets for accelerated breeding in woody plants.Plant cell reports · 2025Review
- Genetic control of seasonal meristem arrest in trees.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- A transcriptional roadmap of the yearly growth cycle in Populus trees.The Plant cell · 2025Article
- Phytochrome B and phytochrome-interacting-factor4 modulate tree seasonal growth in cold environments.Nature communications · 2025Article
- Nature's Master of Ceremony: TheNpj biological timing and sleep · 2025Article
- Wake up: the regulation of dormancy release and bud break in perennial plants.Frontiers in plant science · 2025Review
- Evolution of major flowering pathway integrators in Orchidaceae.Plant reproduction · 2024Article
- Core clock genes adjust growth cessation time to day-night switches in poplar.Nature communications · 2024Article
- Genome-Wide Analysis of theInternational journal of molecular sciences · 2023Article
- Functional diversification and molecular mechanisms of FLOWERING LOCUS T/TERMINAL FLOWER 1 family genes in horticultural plants.Molecular horticulture · 2022Review
- Current status and trends in forest genomics.Forestry research · 2022Review
- Article
- Overexpression of PvCO1, a bamboo CONSTANS-LIKE gene, delays flowering by reducing expression of the FT gene in transgenic Arabidopsis.BMC plant biology · 2018Article
- A Global View of Transcriptome Dynamics During Male Floral Bud Development in Populus tomentosa.Scientific reports · 2018Article
- Photoperiodic Regulation of Shoot Apical Growth in Poplar.Frontiers in plant science · 2018Article
- Isolation and functional characterization of a circadian-regulated CONSTANS homolog (GbCO) from Ginkgo biloba.Plant cell reports · 2017Article
- Changing Responses to Changing Seasons: Natural Variation in the Plasticity of Flowering Time.Plant physiology · 2017Review
- Identification of LATE BLOOMER2 as a CYCLING DOF FACTOR Homolog Reveals Conserved and Divergent Features of the Flowering Response to Photoperiod in Pea.The Plant cell · 2016Article
- Evolution of CONSTANS Regulation and Function after Gene Duplication Produced a Photoperiodic Flowering Switch in the Brassicaceae.Molecular biology and evolution · 2015Article
Corrections and comments
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Authors and funding
10 authors at 7 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
CONSTANS (CO) is an important flowering-time gene in the photoperiodic flowering pathway of annual Arabidopsis thaliana in which overexpression of CO induces early flowering, whereas mutations in CO cause delayed flowering. The closest homologs of CO in woody perennial poplar (Populus spp.) are CO1 and CO2. A previous report showed that the CO2/FLOWERING LOCUS T1 (FT1) regulon controls the onset of reproduction in poplar, similar to what is seen with the CO/FLOWERING LOCUS T (FT) regulon in Arabidopsis. The CO2/FT1 regulon was also reported to control fall bud set. Our long-term field observations show that overexpression of CO1 and CO2 individually or together did not alter normal reproductive onset, spring bud break, or fall dormancy in poplar, but did result in smaller trees when compared with controls. Transcripts of CO1 and CO2 were normally most abundant in the growing season and rhythmic within a day, peaking at dawn. Our manipulative experiments did not provide evidence for transcriptional regulation being affected by photoperiod, light intensity, temperature, or water stress when transcripts of CO1 and CO2 were consistently measured in the morning. A genetic network analysis using overexpressing trees, microarrays, and computation demonstrated that a majority of functionally known genes downstream of CO1 and CO2 are associated with metabolic processes, which could explain their effect on tree size. In conclusion, the function of CO1 and CO2 in poplar does not appear to overlap with that of CO from Arabidopsis, nor do our data support the involvement of CO1 and CO2 in spring bud break or fall bud set.
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