Evidence map›Paper›PMID 23028381›Full record

ArticlePLoS genetics2012

Heterozygous mutations in DNA repair genes and hereditary breast cancer: a question of power.

Nathan A Ellis, Kenneth Offit

Abstract readComment
In one paragraph

Article in PLoS genetics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. RECQL: a new breast cancer susceptibility gene.Cell cycle (Georgetown, Tex.) · 2015
    Article
  5. Review
  6. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Nathan A EllisDepartment of Pediatrics and the Institute of Human Genetics, University of Illinois at Chicago, Chicago, Illinois, United States of America. naellis@uic.edu
Kenneth Offit

Funding

Genetic risk factors in African American colorectal cancer patientsU01CA153060 · NCI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI ELLIS, NATHAN A. · 2010 to 2014
$1.7M
Regulation of Homologous Recombination in Human CellsR01CA140804 · NCI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI ELLIS, NATHAN A. · 2011 to 2015
$1.6M
NCI NIH HHS R01 CA140804NCI NIH HHS R01CA140804NCI NIH HHS U01 CA153060NCI NIH HHS U01CA153060
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Breast NeoplasmsFanconi Anemia Complementation Group C ProteinFemaleHumansRecQ HelicasesSequence DeletionBloom syndrome proteinFANCC protein, humanFanconi Anemia Complementation Group C ProteinRecQ Helicases

Identifiers

PMID23028381
PMCPMC3459983

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.