ReviewThe Journal of physiology2013
The information content of physiological and epileptic brain activity.
Review in The Journal of physiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 26 citations in OpenAlex.
- HyEpiSeiD: a hybrid convolutional neural network and gated recurrent unit model for epileptic seizure detection from electroencephalogram signals.Brain informatics · 2024Article
- Repeated hippocampal seizures lead to brain-wide reorganization of circuits and seizure propagation pathways.Neuron · 2022Article
- Mechanisms for Cognitive Impairment in Epilepsy: Moving Beyond Seizures.Frontiers in neurology · 2022Review
- Impact of GABAThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Decreased Intrinsic Neural Timescales in Mesial Temporal Lobe Epilepsy.Frontiers in human neuroscience · 2021Article
- Changes of Ictal-Onset Epileptic Network Synchronicity in Childhood Absence Epilepsy: A Magnetoencephalography Study.Frontiers in neurology · 2020Article
- Transient Cognitive Impairment in Epilepsy.Frontiers in molecular neuroscience · 2018Article
- Epileptiform activity in the mouse visual cortex interferes with cortical processing in connected areas.Scientific reports · 2017Article
- Integrative properties and transfer function of cortical neurons initiating absence seizures in a rat genetic model.The Journal of physiology · 2016Article
- Information in pallidal neurons increases with parkinsonian severity.Parkinsonism & related disorders · 2015Article
- Single unit action potentials in humans and the effect of seizure activity.Brain : a journal of neurology · 2015Article
- Gain control through divisive inhibition prevents abrupt transition to chaos in a neural mass model.Physical review. E, Statistical, nonlinear, and soft matter physics · 2015Article
- Subthalamic deep brain stimulation reduces pathological information transmission to the thalamus in a rat model of parkinsonism.Frontiers in neural circuits · 2015Article
- Deep brain stimulation of the subthalamic nucleus reestablishes neuronal information transmission in the 6-OHDA rat model of parkinsonism.Journal of neurophysiology · 2014Article
- Why do some brains seize? Molecular, cellular and network mechanisms.The Journal of physiology · 2013Article
Corrections and comments
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Authors and funding
5 authors at 5 institutions in 3 countries.
Funding
Abstract
Cerebral cortex is a highly sophisticated computing machine, feeding on information provided by the senses, which is integrated with other, internally generated patterns of neural activity, to trigger behavioural outputs. Bit by bit, we are coming to understand how this may occur, but still, the nature of the 'cortical code' remains one of the greatest challenges in science. As with other great scientific challenges of the past, fresh insights have come from a coalescence of different experimental and theoretical approaches. These theoretical considerations are typically reserved for cortical function rather than cortical pathology. This approach, though, may also shed light on cortical dysfunction. The particular focus of this review is epilepsy; we will argue that the information capacity of different brain states provides a means of understanding, and even assessing, the impact and locality of the epileptic pathology. Epileptic discharges, on account of their all-consuming and stereotyped nature, represent instances where the information capacity of the network is massively compromised. These intense discharges also prevent normal processing in surrounding territories, but in a different way, through enhanced inhibition in these territories. Information processing is further compromised during the period of post-ictal suppression, during interictal bursts, and also at other times, through more subtle changes in synaptic function. We also comment on information processing in other more physiological brain states.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.