ArticleCytoskeleton (Hoboken, N.J.)2013
Modulation of Golgi-associated microtubule nucleation throughout the cell cycle.
Article in Cytoskeleton (Hoboken, N.J.), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 36 citations in OpenAlex.
- Insights into Microtubule Nucleation at the Golgi Apparatus.Sub-cellular biochemistry · 2026Review
- Experimental Tools and Techniques for Studying Microtubule Nucleation at the Centrosome and the Golgi Apparatus.Methods in molecular biology (Clifton, N.J.) · 2026Article
- CLASP1/2 regulate immune synapse maturation in natural killer cells.Journal of leukocyte biology · 2025Article
- Microtubule nucleation and γTuRC centrosome localization in interphase cells require ch-TOG.Nature communications · 2023Article
- Review
- Neuroprogenitor Cells From Patients With TBCK Encephalopathy Suggest Deregulation of Early Secretory Vesicle Transport.Frontiers in cellular neuroscience · 2021Article
- Regulation of Glucose-Dependent Golgi-Derived Microtubules by cAMP/EPAC2 Promotes Secretory Vesicle Biogenesis in Pancreatic β Cells.Current biology : CB · 2019Article
- Spatial and proteomic profiling reveals centrosome-independent features of centriolar satellites.The EMBO journal · 2019Article
- Organelle Inheritance Control of Mitotic Entry and Progression: Implications for Tissue Homeostasis and Disease.Frontiers in cell and developmental biology · 2019Review
- Integrin and microtubule crosstalk in the regulation of cellular processes.Cellular and molecular life sciences : CMLS · 2018Review
- The dual role of the centrosome in organizing the microtubule network in interphase.EMBO reports · 2018Article
- Nonrandom γ-TuNA-dependent spatial pattern of microtubule nucleation at the Golgi.Molecular biology of the cell · 2017Article
- The catalytic subunit of DNA polymerase δ inhibits γTuRC activity and regulates Golgi-derived microtubules.Nature communications · 2017Article
- Actin- and microtubule-dependent regulation of Golgi morphology by FHDC1.Molecular biology of the cell · 2016Article
- Mto2 multisite phosphorylation inactivates non-spindle microtubule nucleation complexes during mitosis.Nature communications · 2015Article
- Nucleation and Dynamics of Golgi-derived Microtubules.Frontiers in neuroscience · 2015Review
- The centrosome-Golgi apparatus nexus.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2014Review
- Golgi as an MTOC: making microtubules for its own good.Histochemistry and cell biology · 2013Review
- Ice recovery assay for detection of Golgi-derived microtubules.Methods in cell biology · 2013Article
- Signaling at the Golgi during mitosis.Methods in cell biology · 2013Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
Abstract
A microtubule (MT) subpopulation that emanates from Golgi membrane has been recently shown to comprise a significant part of MT network in interphase cells. In this study, we address whether Golgi membrane, which is being extensively remodeled throughout the cell cycle, retains its ability to nucleate MTs at diverse cell cycle stages. Live cell imaging and immunofluorescence microscopy reveals that Golgi-derived MTs form at multiple stages of the cell cycle, including G(1), G(2), and distinct phases of mitosis. However, the capacity of Golgi to nucleate MTs in mitosis is strongly down-regulated as compared with interphase, indicating that this property is cell cycle regulated. We demonstrate that Golgi-derived MTs are indispensable for efficient Golgi assembly in telophase, and speculate that these noncentrosomal MTs may hold specific functions at other cell cycle stages.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.