Evidence map›Paper›PMID 23027291›Full record

ArticleOptics letters2012

Molecular layer detection on a diffractive optical balance.

Xuefeng Wang, Ming Zhao, David D Nolte

Abstract read
In one paragraph

Article in Optics letters, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Xuefeng WangDepartment of Physics, Purdue University, West Lafayette, Indiana 47907, USA.
Ming Zhao
David D Nolte

Funding

Immunomagnetic Diffractometry for Rapid Biomolecular DetectionR21EB008154 · NIBIB · PURDUE UNIVERSITY · PI SAVRAN, CAGRI · 2008 to 2009
$405k
Multiplexed Assays on the BioCD for Acute Lymphocytic LeukemiaR21CA125336 · NCI · PURDUE UNIVERSITY · PI NOLTE, DAVID D · 2008 to 2009
$392k
NCI NIH HHS 5R21CA125336-02NCI NIH HHS R21 CA125336NIBIB NIH HHS 1R21EB008154-01A1NIBIB NIH HHS R21 EB008154
6 · The paper itself

Abstract

Diffraction-based molecular detection is achieved by etching optical gratings into thermal oxide on silicon. The gratings perform as a stable common-path diffractive optical balance (DOB) designed to operate near a missing diffraction order. The biosensor is operated in an off-null condition with a phase bias to produce a high-contrast responsivity that is linear in accumulated molecules but with a low background. The DOB linear responsivity is a factor of 20 larger than the reflectometric responsivity of planar thermal oxide.

Indexed as

Optical PhenomenaAnimalsBiosensing TechniquesImmunoglobulin GLasersRabbitsSignal-To-Noise RatioSiliconImmunoglobulin GSilicon

Identifiers

PMID23027291
PMCPMC4028713

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.