Evidence map›Paper›PMID 23027187›Full record

ArticleAntimicrobial agents and chemotherapy2012

A case of daptomycin-induced immune thrombocytopenia.

Charles Grégoire, Caren Brumpt, Delphine Loirat, Nicolas Lau, Cedric Bruel, Francois Philippart, Carine Couzigou, Maité Garrouste-Orgeas, Benoit Misset

Open access · bronzeAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Charles GrégoireIntensive Care Unit, Saint Joseph Hospital Network, Paris, France. charles.gregoire@gmail.com
Caren Brumpt
Delphine Loirat
Nicolas Lau
Cedric Bruel
Francois Philippart
Carine Couzigou
Maité Garrouste-Orgeas
Benoit Misset
St. Joseph Hospital · USDélégation Paris 5 · FRHôpital Lariboisière · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a case of severe daptomycin-induced immune thrombocytopenia in a patient treated for methicillin-resistant Staphylococcus epidermidis and ampicillin-resistant Enterococcus faecalis bacteremia acquired in an intensive care unit. Serum antibodies bound to platelets in the presence of daptomycin on flow cytometry. There was no evidence of other causes of thrombocytopenia. The patient died of brain herniation complicating extensive cerebral hemorrhage. To our knowledge, this is the first described case of daptomycin-induced thrombocytopenia.

Indexed as

Abdominal AbscessAmpicillin ResistanceAnti-Bacterial AgentsDaptomycinEnterococcus faecalisFatal OutcomeFlow CytometryGram-Positive Bacterial InfectionsHumansIntracranial HemorrhagesMaleMesenteric VeinsMethicillin-Resistant Staphylococcus aureusMiddle AgedPlatelet TransfusionPseudomonas InfectionsAnti-Bacterial AgentsDaptomycin

Identifiers

PMID23027187
PMCPMC3497155
OpenAlexW1997094749

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.