ArticlePloS one2012
Listeria monocytogenes differential transcriptome analysis reveals temperature-dependent Agr regulation and suggests overlaps with other regulons.
Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed, 57 citations in OpenAlex.
- Transcriptional responses of Listeria monocytogenes to low-temperature stress reveal distinct adaptive mechanisms in the absence of BKD and PrfA activation.Microbial pathogenesis · 2025Article
- Effect of Temperature, Surface, and Medium Qualities on the Biofilm Formation ofFoods (Basel, Switzerland) · 2025Article
- The type of food influences the behaviour of Listeria monocytogenes in a food-gastrointestinal-infection model.NPJ science of food · 2025Article
- Lactic acid bacteria secreted proteins as potential Listeria monocytogenes quorum sensing inhibitors.Molecular diversity · 2024Article
- A short-lived peptide signal regulates cell-to-cell communication in Listeria monocytogenes.Communications biology · 2024Article
- Characterization of an Autoinducing Peptide Signal Reveals Highly Efficacious Synthetic Inhibitors and Activators of Quorum Sensing and Biofilm Formation inBiochemistry · 2023Article
- Article
- Rhizobacteria Impact Colonization of Listeria monocytogenes on Arabidopsis thaliana Roots.Applied and environmental microbiology · 2021Article
- Analysis of temporal gene regulation of Listeria monocytogenes revealed distinct regulatory response modes after exposure to high pressure processing.BMC genomics · 2021Article
- Transcriptomic and Phenotypic Analyses of the Sigma B-Dependent Characteristics and the Synergism between Sigma B and Sigma L inMicroorganisms · 2020Article
- Links between S-adenosylmethionine and Agr-based quorum sensing for biofilm development in Listeria monocytogenes EGD-e.MicrobiologyOpen · 2020Article
- Review
- The σRNA biology · 2019Article
- Characterization of the biofilm phenotype of a Listeria monocytogenes mutant deficient in agr peptide sensing.MicrobiologyOpen · 2019Article
- MouR controls the expression of the Listeria monocytogenes Agr system and mediates virulence.Nucleic acids research · 2018Article
- Chitinase Expression in Listeria monocytogenes Is Influenced byApplied and environmental microbiology · 2017Article
- Listeria monocytogenes encodes a functional ESX-1 secretion system whose expression is detrimental to in vivo infection.Virulence · 2017Article
- Transcriptomic Analysis of the Adaptation ofFrontiers in microbiology · 2017Article
- Listeria monocytogenes σH Contributes to Expression of Competence Genes and Intracellular Growth.Journal of bacteriology · 2016Article
- Identification of the agr Peptide of Listeria monocytogenes.Frontiers in microbiology · 2016Article
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Listeria monocytogenes is a ubiquitous, opportunistic pathogenic organism. Environmental adaptation requires constant regulation of gene expression. Among transcriptional regulators, AgrA is part of an auto-induction system. Temperature is an environmental cue critical for in vivo adaptation. In order to investigate how temperature may affect AgrA-dependent transcription, we compared the transcriptomes of the parental strain L. monocytogenes EGD-e and its ΔagrA mutant at the saprophytic temperature of 25°C and in vivo temperature of 37°C. Variations of transcriptome were higher at 37°C than at 25°C. Results suggested that AgrA may be involved in the regulation of nitrogen transport, amino acids, purine and pyrimidine biosynthetic pathways and phage-related functions. Deregulations resulted in a growth advantage at 37°C, but affected salt tolerance. Finally, our results suggest overlaps with PrfA, σB, σH and CodY regulons. These overlaps may suggest that through AgrA, Listeria monocytogenes integrates information on its biotic environment.
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