ArticleEvidence-based complementary and alternative medicine : eCAM2012
Virgin coconut oil supplementation prevents bone loss in osteoporosis rat model.
Article in Evidence-based complementary and alternative medicine : eCAM, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 58 citations in OpenAlex.
- Cocos nucifera (L.) (Arecaceae): A phytochemical and pharmacological review.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2015Pooled it
- Virgin coconut oil: A comprehensive review of its health impacts and functional food applications.Food chemistry: X · 2026Review
- Protective role of virgin coconut oil on potent biochemical biomarkers in Wistar rat model of comorbid depression.Journal of advanced veterinary and animal research · 2024Article
- Saturated Fatty Acids and Omega-3 Polyunsaturated Fatty Acids Improve Metabolic Parameters in Ovariectomized Female Mice.Endocrinology · 2023Article
- Coconut Oil Saturated Fatty Acids Improved Energy Homeostasis but not Blood Pressure or Cognition in VCD-Treated Female Mice.Endocrinology · 2023Article
- Protective Effect of Virgin Coconut Oil on Osteopenia Induced by High Refined Carbohydrate-Containing Diet in Mice.Foods (Basel, Switzerland) · 2022Article
- Anti-arthritic effect of chicken embryo tissue hydrolyzate against adjuvant arthritis in rats (X-ray microtomographic and histopathological analysis).Food science & nutrition · 2021Article
- The Glucose-Lowering Effects of Coconut Oil: A Case Report and Review of the Literature.Case reports in endocrinology · 2020Article
- Combined virgin coconut oil and tocotrienol-rich fraction protects against bone loss in osteoporotic rat model.Veterinary world · 2019Article
- Protective effects of honey by bees (Veterinary world · 2019Article
- Article
- Preventive effects of collagen Peptide from deer sinew on bone loss in ovariectomized rats.Evidence-based complementary and alternative medicine : eCAM · 2014Article
- Tibia bone properties at different time course of ovariectomized rats.Journal of diabetes and metabolic disorders · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Oxidative stress and free radicals have been implicated in the pathogenesis of osteoporosis. Therefore, antioxidant compounds have the potential to be used in the prevention and treatment of the disease. In this study, we investigated the effects of virgin coconut oil (VCO) on bone microarchitecture in a postmenopausal osteoporosis rat model. VCO is a different form of coconut oil as it is rich with antioxidants. Three-month-old female rats were randomly grouped into baseline, sham-operated, ovariectomized control (Ovx), and ovariectomized rats fed with 8% VCO in their diet for six weeks (Ovx+VCO). Bone histomorphometry of the right femora was carried out at the end of the study. Rats supplemented with VCO had a significantly greater bone volume and trabecular number while trabecular separation was lower than the Ovx group. In conclusion, VCO was effective in maintaining bone structure and preventing bone loss in estrogen-deficient rat model.
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Registered trials
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