ArticleClinical journal of the American Society of Nephrology : CJASN2012
Response to dietary oxalate after bariatric surgery.
Article in Clinical journal of the American Society of Nephrology : CJASN, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed, 52 citations in OpenAlex.
- Kidney stone disease: risk factors, pathophysiology and management.Nature reviews. Nephrology · 2025Review
- Dietary advice for patients with bowel-related conditions and malabsorption.World journal of urology · 2023Review
- Secondary oxalate nephropathy and impact of high-dose vitamin C intake for COVID-19 prevention on a patient with Roux-en-Y gastric bypass: A case report.Clinical case reports · 2023Article
- The Beneficial Effects of Bariatric-Surgery-Induced Weight Loss on Renal Function.Metabolites · 2022Review
- Renal Function Following Bariatric Surgery: a Literature Review of Potential Mechanisms.Obesity surgery · 2022Review
- Bariatric Metabolic Surgery Reduced Liver Enzyme Levels in Patients with Non-Alcohol Fatty Liver Disease.Kansas journal of medicine · 2021Article
- Article
- Review
- Food intake biomarkers for green leafy vegetables, bulb vegetables, and stem vegetables: a review.Genes & nutrition · 2020Review
- A Successful Approach to Kidney Transplantation in Patients With Enteric (Secondary) Hyperoxaluria.Transplantation direct · 2017Article
- Hyperoxaluria in a Model of Mini-Gastric Bypass Surgery in Rats.Obesity surgery · 2017Article
- Oxalobacter formigenes colonization normalizes oxalate excretion in a gastric bypass model of hyperoxaluria.Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · 2017Article
- Kidney disease and obesity: epidemiology, mechanisms and treatment.Nature reviews. Nephrology · 2017Review
- Kidney Stones After Bariatric Surgery: Risk Assessment and Mitigation.Bariatric surgical practice and patient care · 2017Review
- Urolithiasis in inflammatory bowel disease and bariatric surgery.World journal of nephrology · 2016Article
- Review
- The management of patients with enteric hyperoxaluria.Urolithiasis · 2016Review
- Stone formation and management after bariatric surgery.Nature reviews. Urology · 2015Review
- Nephropathy in dietary hyperoxaluria: A potentially preventable acute or chronic kidney disease.World journal of nephrology · 2014Review
- Kidney stone risk following Roux-en-Y gastric bypass surgery.Translational andrology and urology · 2014Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
objectivesBariatric surgery (BS) may be associated with increased oxalate excretion and a higher risk of nephrolithiasis. This study aimed to investigate urinary abnormalities and responses to an acute oxalate load as an indirect assessment of the intestinal absorption of oxalate in this population. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: Twenty-four-hour urine specimens were collected from 61 patients a median of 48 months after BS (post-BS) as well as from 30 morbidly obese (MO) participants; dietary information was obtained through 24-hour food recalls. An oral oxalate load test (OLT), consisting of 2-hour urine samples after overnight fasting and 2, 4, and 6 hours after consuming 375 mg of oxalate (spinach juice), was performed on 21 MO and 22 post-BS patients 12 months after BS. Ten post-BS patients also underwent OLT before surgery (pre-BS).
resultsThere was a higher percentage of low urinary volume (<1.5 L/d) in post-BS versus MO (P<0.001). Hypocitraturia and hyperoxaluria (P=0.13 and P=0.36, respectively) were more frequent in BS versus MO patients. The OLT showed intragroup (P<0.001 for all periods versus baseline) and intergroup differences (P<0.001 for post-BS versus MO; P=0.03 for post-BS versus pre-BS). The total mean increment in oxaluria after 6 hours of load, expressed as area under the curve, was higher in both post-BS versus MO and in post-BS versus pre-BS participants (P<0.001 for both).
conclusionsThe mean oxaluric response to an oxalate load is markedly elevated in post-bariatric surgery patients, suggesting that increased intestinal absorption of dietary oxalate is a predisposing mechanism for enteric hyperoxaluria.
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