Evidence map›Paper›PMID 23024135›Full record

ArticleAmerican journal of epidemiology2012

Does shared family background influence the impact of educational differences on early mortality?

Grethe Søndergaard, Laust H Mortensen, Anne-Marie Nybo Andersen, Per Kragh Andersen, Susanne Oksbjerg Dalton, Mia Madsen, Merete Osler

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in American journal of epidemiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Grethe SøndergaardResearch Centre for Prevention and Health, Glostrup University Hospital, Glostrup, Germany. gsoe0038@regionh.dk
Laust H Mortensen
Anne-Marie Nybo Andersen
Per Kragh Andersen
Susanne Oksbjerg Dalton
Mia Madsen
Merete Osler

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The mechanisms behind social differences in mortality rates have been debated. The authors examined the extent to which shared family background and health in early life could explain the association between educational status and all-cause mortality rates using a sibling design. The study was register-based and included all individuals born in Denmark between 1950 and 1979 who had at least 1 full sibling born in the same time period (n = 1,381,436). All individuals were followed from 28 years of age until death, emigration, or December 2009. The authors used Cox regression analyses to estimate hazard ratios for mortality according to educational level. Conventional cohort and intersibling analyses were carried out and conducted separately for deaths occurring before and after the age of 45 years, respectively. The cohort analyses showed an inverse association between educational status and all-cause mortality that was strongest for males, increased with younger birth cohorts, and tended to be strongest in the analyses of death before 45 years of age. The associations were attenuated slightly in the intersibling analyses and after adjustment for serious health conditions in early life. Hence, health selection and confounding by factors shared by siblings explained only a minor part of the association between educational level and all-cause mortality.

Indexed as

Cause of DeathEducational StatusFamilyHealth Status DisparitiesPovertySiblingsAdultAlgorithmsDenmarkFemaleFollow-Up StudiesHumansIncidenceMaleMiddle AgedNeoplasms

Identifiers

PMID23024135

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.