ArticleMagnetic resonance in medicine2012
Rapid 3D-imaging of phosphocreatine recovery kinetics in the human lower leg muscles with compressed sensing.
Article in Magnetic resonance in medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed.
- Dynamic multivoxel-localizedNMR in biomedicine · 2018Trial
- Three-dimensional mapping of the creatine kinase enzyme reaction rate in muscles of the lower leg.NMR in biomedicine · 2013Trial
- High-Resolution 3D Turbo Spin-Echo Wrist MRI at 7T Accelerated by Compressed Sensing.NMR in biomedicine · 2025Article
- DynamicScientific reports · 2021Article
- Musculoskeletal MR Imaging Applications at Ultra-High (7T) Field Strength.Magnetic resonance imaging clinics of North America · 2021Review
- High-Resolution DynamicIEEE transactions on bio-medical engineering · 2020Article
- Phosphorus magnetic resonance spectroscopic imaging using flyback echo planar readout trajectories.Magma (New York, N.Y.) · 2018Article
- Oxidative capacity varies along the length of healthy human tibialis anterior.The Journal of physiology · 2018Article
- Dynamic phosphocreatine imaging with unlocalized pH assessment of the human lower leg muscle following exercise at 3T.Magnetic resonance in medicine · 2018Article
- Assessing tissue metabolism by phosphorous-31 magnetic resonance spectroscopy and imaging: a methodology review.Quantitative imaging in medicine and surgery · 2017Review
- Considerations in applying compressed sensing to in vivo phosphorus MR spectroscopic imaging of human brain at 3T.Medical & biological engineering & computing · 2017Article
- In-vivoAnalytical biochemistry · 2017Review
- DynamicNMR in biomedicine · 2016Article
- Mitochondrial function assessed by 31P MRS and BOLD MRI in non-obese type 2 diabetic rats.Physiological reports · 2016Article
- Magnetic Resonance Imaging of Phosphocreatine and Determination of BOLD Kinetics in Lower Extremity Muscles using a Dual-Frequency Coil Array.Scientific reports · 2016Article
- Sparse Reconstruction Techniques in Magnetic Resonance Imaging: Methods, Applications, and Challenges to Clinical Adoption.Investigative radiology · 2016Review
- Compressed sensing MRI: a review of the clinical literature.The British journal of radiology · 2015Review
- 3D-mapping of phosphocreatine concentration in the human calf muscle at 7 T: comparison to 3 T.Magnetic resonance in medicine · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
The rate of phosphocreatine (PCr) resynthesis following physical exercise is an accepted index of mitochondrial oxidative metabolism and has been studied extensively with unlocalized (31)P-MRS methods and small surface coils. Imaging experiments using volume coils that measure several muscles simultaneously can provide new insights into the variability of muscle function in healthy and diseased states. However, they are limited by long acquisition times relative to the dynamics of PCr recovery. This work focuses on the implementation of a compressed sensing technique to accelerate imaging of PCr resynthesis following physical exercise, using a modified three-dimensional turbo-spin-echo sequence and principal component analysis as sparsifying transform. The compressed sensing technique was initially validated using 2-fold retrospective undersampling of fully sampled data from four volunteers acquired on a 7T MRI system (voxel size: 1.6 mL, temporal resolution: 24 s), which led to an accurate estimation of the mono-exponential PCr resynthesis rate constant (mean error <6.4%). Acquisitions with prospective 2-fold acceleration (temporal resolution: 12 s) demonstrated that three-dimensional mapping of PCr resynthesis is possible at a temporal resolution that is sufficiently high for characterizing the recovery curve of several muscles in a single measurement.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.