Evidence map›Paper›PMID 23023505›Full record

ArticleCirculation research2012

Nitroxyl, redox switches, cardiac myofilaments, and heart failure: a prequel to novel therapeutics?

Ying Ge, Richard L Moss

Abstract readEditorialComment
In one paragraph

Article in Circulation research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Para-SubstitutedMolecules (Basel, Switzerland) · 2022
    Article
  3. Review
  4. Cardiovascular diagnosis and therapy · 2020
    Article
  5. Review
  6. The chemical biology of HNO signaling.Archives of biochemistry and biophysics · 2017
    Review
  7. Review
  8. Nitroxyl (HNO) for treatment of acute heart failure.Current heart failure reports · 2014
    Review
  9. Nitroxyl accelerates the oxidation of oxyhemoglobin by nitrite.Nitric oxide : biology and chemistry · 2013
    Article
  10. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Ying Ge
Richard L Moss

Funding

My-BP-C Modulation of Cardiac ContractionR37HL082900 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI MOSS, RICHARD L · 2006 to 2015
$6.0M
Top Down Proteomics Of Myofilaments In Heart FailureR01HL096971 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI GE, YING · 2011 to 2021
$3.3M
NHLBI NIH HHS R01 HL096971NHLBI NIH HHS R01HL096971NHLBI NIH HHS R37 HL082900NHLBI NIH HHS R37 HL82900
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsDisulfidesMyocardial ContractionMyocytes, CardiacMyofibrilsNitrogen OxidesDisulfidesNitrogen Oxidesnitroxyl

Identifiers

PMID23023505
PMCPMC3494458

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.