ReviewAmerican journal of kidney diseases : the official journal of the National Kidney Foundation2012
CKiD (CKD in children) prospective cohort study: a review of current findings.
Review in American journal of kidney diseases : the official journal of the National Kidney Foundation, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00327860 (Chronic Kidney Disease in Children Prospective Cohort Study), which is not on this map. Cited by 116 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Chronic Kidney Disease in Children Prospective Cohort Study (CKiD)
Who cites it
116 citing papers in PubMed, 3 syntheses or guidelines pooled it, 241 citations in OpenAlex.
- Pooled it
- Environmental exposures and pediatric kidney function and disease: A systematic review.Environmental research · 2017Pooled it
- Impact of chronic kidney disease on health-related quality of life in the pediatric population: meta-analysis.Jornal de pediatriaPooled it
- Baseline characteristics of participants in the NAVKIDSPediatric nephrology (Berlin, Germany) · 2023Trial
- Effect of L-carnitine supplementation on lipid profile and apolipoproteins in children on hemodialysis: a randomized placebo-controlled clinical trial.Pediatric nephrology (Berlin, Germany) · 2021Trial
- Characterizing children with chronic kidney disease and severe proteinuria in the United States: a retrospective analysis using electronic health records.Pediatric nephrology (Berlin, Germany) · 2026Article
- Association between estimated time with low glomerular filtration rate and access to transplant among youth with advanced chronic kidney disease.Pediatric nephrology (Berlin, Germany) · 2026Article
- Association of UACR and UPCR with kidney failure: analysis of observational data in children with chronic kidney disease.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2026Observational
- Profile of FGF23 and NTproBNP levels and their association with left ventricular hypertrophy in children and adolescents with CKD.International urology and nephrology · 2026Article
- De novo HLA antibodies after blood transfusion and/or kidney transplant in children with kidney disease.Pediatric nephrology (Berlin, Germany) · 2026Article
- Bridging Borders: Addressing Inequities in Pediatric Kidney Care for Hispanic and Immigrant Children.Journal of immigrant and minority health · 2026Article
- Dual knowledge-guided data augmentation for robust clinical prediction models.Scientific reports · 2026Article
- Implementation of a Novel Patient-Reported Outcome Measure for the Assessment of Symptoms in Children Living With Chronic Kidney Disease (PRO-Kid)-Program Report.Canadian journal of kidney health and disease · 2026Article
- Reevaluating the role of calcitriol therapy in the reduction of proteinuria in children with chronic kidney disease.International urology and nephrology · 2026Article
- Neurodevelopmental Outcomes in Early Childhood Chronic Kidney Disease: Evidence from a Case-control StudyAnnals of neurosciences · 2025Article
- A Within-Trial Economic Evaluation of a Patient Navigator Program in Children With CKD.Kidney international reports · 2025Article
- Biomarker Panels for Discriminating Risk of CKD Progression in Children.Journal of the American Society of Nephrology : JASN · 2025Article
- Pediatric Chronic Kidney Disease: Mind the Gap Between Reality and Expectations.Children (Basel, Switzerland) · 2025Review
- Investigation of a targeted panel of gut microbiome-derived toxins in children with chronic kidney disease.Pediatric nephrology (Berlin, Germany) · 2025Article
- Particularities in the "Oldie but Goldie" Tc-99m DMSA Renography: A Retrospective Reference Centre Overview of 931 Children.Diagnostics (Basel, Switzerland) · 2025Article
56 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 5 institutions in 1 country.
Funding
Abstract
Chronic kidney disease (CKD) is a life-long condition associated with substantial morbidity and premature death due to complications from a progressive decrease in kidney function. The incidence and prevalence of all stages of CKD in children continues to increase worldwide. Between 2000 and 2008, the kidney replacement therapy incidence rate in those aged 0-19 years increased 5.9% to 15 per million population, highlighting the importance of CKD research in children. Many comorbid conditions seen in adults with CKD, including cardiovascular disease and cognitive impairment, also are highly prevalent in children, implicitly demonstrating the crucial need for initiating therapy early to improve health outcomes in children with CKD. The CKiD (Chronic Kidney Disease in Children) Study is a prospective cohort study of 586 children aged 1-16 years with an estimated glomerular filtration rate of 30-90 mL/min/1.73 m(2). Since its inception, CKiD has identified risk factors for CKD progression and cardiovascular disease in children with CKD and highlighted the effects of CKD on outcomes unique to children, including neurocognitive development and growth. This review summarizes the findings to date, illustrating the spectrum of CKD-associated complications in children and emphasizing areas requiring further investigation. Taken in sum, these elements stress that initiating treatment at an early age is essential for reducing long-term morbidity and mortality in children with CKD.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.