Evidence map›Paper›PMID 23022353›Full record

ReviewBiotechnology advances

Stable isotope probing in the metagenomics era: a bridge towards improved bioremediation.

Ondrej Uhlik, Mary-Cathrine Leewis, Michal Strejcek, Lucie Musilova, Martina Mackova, Mary Beth Leigh, Tomas Macek

Open access · greenAbstract readReview
In one paragraph

Review in Biotechnology advances. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
8.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 131 citations in OpenAlex.

  1. Applied and environmental microbiology · 2026
    Review
  2. Review
  3. Article
  4. Article
  5. Trophic Position of the White Worm (International journal of molecular sciences · 2024
    Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Stable isotopes of fatty acids: current and future perspectives for advancing trophic ecology.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2020
    Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Rhizosphere Microbiome Modulators: Contributions of Nitrogen Fixing Bacteria towards Sustainable Agriculture.International journal of environmental research and public health · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Ondrej UhlikInstitute of Chemical Technology Prague, Faculty of Food and Biochemical Technology, Department of Biochemistry and Microbiology, Technicka 3, 166 28 Prague, Czech Republic. ondrej.uhlik@vscht.cz
Mary-Cathrine Leewis
Michal Strejcek
Lucie Musilova
Martina Mackova
Mary Beth Leigh
Tomas Macek
University of Chemistry and Technology, Prague · CZUniversity of Alaska Fairbanks · US

Funding

The Administrative CoreP20GM103395 · NIGMS · UNIVERSITY OF ALASKA FAIRBANKS · PI BRIAN M BARNES · 2012 to 2026
$66.1M
VIROLOGISTP20RR016466 · NCRR · UNIVERSITY OF ALASKA FAIRBANKS · PI LEIGH, MARY BETH · 2001 to 2011
$37.0M
NCRR NIH HHS 5P20RR016466-12NCRR NIH HHS P20 RR016466NIGMS NIH HHS 8P20GM103395-12NIGMS NIH HHS P20 GM103395
6 · The paper itself

Abstract

Microbial biodegradation and biotransformation reactions are essential to most bioremediation processes, yet the specific organisms, genes, and mechanisms involved are often not well understood. Stable isotope probing (SIP) enables researchers to directly link microbial metabolic capability to phylogenetic and metagenomic information within a community context by tracking isotopically labeled substances into phylogenetically and functionally informative biomarkers. SIP is thus applicable as a tool for the identification of active members of the microbial community and associated genes integral to the community functional potential, such as biodegradative processes. The rapid evolution of SIP over the last decade and integration with metagenomics provide researchers with a much deeper insight into potential biodegradative genes, processes, and applications, thereby enabling an improved mechanistic understanding that can facilitate advances in the field of bioremediation.

Indexed as

Biodegradation, EnvironmentalCarbonEnvironmental PollutantsIsotope LabelingMetagenomicsPhylogenyCarbonEnvironmental Pollutants

Identifiers

PMID23022353
PMCPMC3578049
OpenAlexW2044735090

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.