ReviewNutrition (Burbank, Los Angeles County, Calif.)2013
Obesity, systemic inflammation, and increased risk for cardiovascular disease and diabetes among adolescents: a need for screening tools to target interventions.
Review in Nutrition (Burbank, Los Angeles County, Calif.), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 119 papers, 5 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
119 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- The Impact of Physical Training on Circulating Retinol-Binding Protein 4: A Systematic Review.Physiological research · 2026Pooled it
- A systematic review and meta-analysis of loss-of-control eating in relation to cardiometabolic health components and inflammatory markers.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2024Pooled it
- Efficacy of Off-Label Therapy for Non-alcoholic Fatty Liver Disease in Improving Non-invasive and Invasive Biomarkers: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials.Frontiers in medicine · 2022Pooled it
- Association Between Eating Speed and Metabolic Syndrome: A Systematic Review and Meta-Analysis.Frontiers in nutrition · 2021Pooled it
- The effect of ginger supplementation on serum C-reactive protein, lipid profile and glycaemia: a systematic review and meta-analysis.Food & nutrition research · 2016Pooled it
- Use of a Metabolic Syndrome SeverityDiabetes care · 2018Trial
- Longitudinal associations between father- and mother-child interactions, coparenting, and child cardiometabolic health.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2026Article
- Prediabetes in children and adolescents: what do we need to know?Annals of pediatric endocrinology & metabolism · 2026Article
- Complication Risk Classification in Children and Adolescents With Type 1 Diabetes: Interpretable Machine Learning Study Based on Saudi Clinical Guidelines.JMIR formative research · 2026Article
- Evaluating home-delivered meal service programs for obesity: a randomized controlled approach.Food & nutrition research · 2026Article
- From gene to plate in Indonesia: a food system framework for the triple burden of malnutrition.Frontiers in public health · 2026Article
- TNF-α/NF-κB mediated upregulation of Dectin-1 in hyperglycemic obesity: implications for metabolic inflammation and diabetes.Journal of translational medicine · 2025Article
- Obesity indices and diabetes risk among hypertensive patients: insights from the China Multi-Ethnicity Cohort study.Frontiers in endocrinology · 2025Article
- Time-restricted feeding improves metabolic syndrome by activating thermogenesis in brown adipose tissue and reducing inflammatory markers.Frontiers in immunology · 2025Article
- Obesity and Polycystic Ovary Syndrome.Journal of obesity & metabolic syndrome · 2024Review
- Socioeconomic Disadvantage, Neighborhood Belonging, and Inflammation Among Adolescents.Psychosomatic medicine · 2024Article
- Longitudinal urinary neopterin is associated with hearing threshold change over time in independent older adults.Scientific reports · 2024Article
- Prediabetes in children and adolescents: A ticking bomb!World journal of clinical pediatrics · 2024Article
- C-reactive protein and high-sensitivity C-reactive protein levels in asymptomatic intestinal parasite carriers from urban and rural areas of Gabon.PLoS neglected tropical diseases · 2024Article
- Tocotrienols Prevent the Decline of Learning Ability in High-Fat, High-Sucrose Diet-Fed C57BL/6 Mice.International journal of molecular sciences · 2024Article
59 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
1 author.
Funding
Abstract
Cardiovascular disease (CVD) and type 2 diabetes mellitus have their roots in childhood, particularly in obese children and adolescents, raising important opportunities for early lifestyle intervention in at-risk individuals. However, not all obese individuals are at the same risk for disease progression. Accurate screening of obese adolescents may identify those in greatest need for intensive intervention to prevent or delay future disease. One potential screening target is obesity-related inflammation, which contributes to insulin resistance, metabolic syndrome, and CVD. In adults, the inflammatory marker high-sensitivity C-reactive protein (hsCRP) has utility for risk stratification and treatment initiation in individuals of intermediate CVD risk. In adolescents, hsCRP shares many of the associations of hsCRP in adults regarding the degree of insulin resistance, metabolic syndrome, and carotid artery media thickness. However, long-term data linking increased hsCRP levels-and increased insulin or decreased adiponectin-in childhood to adult disease outcomes are lacking at this time. Future efforts continue to be needed to identify childhood clinical and laboratory characteristics that could be used as screening tests to predict adult disease progression. Such tests may have utility in motivating physicians and patients' families toward lifestyle changes, ultimately improving prevention efforts.
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