ArticleThe Journal of urology2013
Microcomposition of human urinary calculi using advanced imaging techniques.
Article in The Journal of urology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 32 citations in OpenAlex.
- The key role of major and trace elements in the formation of five common urinary stones.BMC urology · 2024Article
- Significance of TRPV5 and OPN biomarker levels in clinical diagnosis of patients with early urinary calculi.American journal of translational research · 2021Article
- Analysis of stones formed in the human gall bladder and kidney using advanced spectroscopic techniques.Biophysical reviews · 2020Review
- Kidney stone analysis techniques and the role of major and trace elements on their pathogenesis: a review.Biophysical reviews · 2014Article
- Nanouric acid or nanocalcium phosphate as central nidus to induce calcium oxalate stone formation: a high-resolution transmission electron microscopy study on urinary nanocrystallites.International journal of nanomedicine · 2014Article
- Pathogenesis of nephrolithiasis.The Journal of urology · 2013Article
- New insights into the pathogenesis of renal calculi.The Urologic clinics of North America · 2013Review
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
Abstract
purposeCommon methods of commercial urolithiasis analysis, such as light microscopy and Fourier transform infrared spectroscopy, provide limited or no information on the molecular composition of stones, which is vital when studying early stone pathogenesis. We used synchrotron radiation based microfocused x-ray fluorescence, x-ray absorption and x-ray diffraction advanced imaging techniques to identify and map the elemental composition, including trace elements, of urinary calculi on a μm (0.0001 cm) scale. MATERIALS AND
methodsHuman stone samples were obtained during serial percutaneous nephrolithotomy and ureteroscopy procedures. A portion of each sample was sent for commercial stone analysis and a portion was retained for synchrotron radiation based advanced imaging analysis.
resultsSynchrotron radiation based methods of stone analysis correctly identified stone composition and provided additional molecular detail on elemental components and spatial distribution in uroliths. Resolution was on the order of a few μm.
conclusionsKnowledge of all elements present in lithogenesis at this detail allows for better understanding of early stone formation events, which may provide additional insight to prevent and treat stone formation.
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Registered trials
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