ReviewPsychoneuroendocrinology2013
Twenty-five years of research on the behavioural malaise associated with influenza and the common cold.
Review in Psychoneuroendocrinology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 39 citations in OpenAlex.
- Meditation or exercise for preventing acute respiratory infection (MEPARI-2): A randomized controlled trial.PloS one · 2018Trial
- Effects of upper respiratory tract illnesses, ibuprofen and caffeine on reaction time and alertness.Psychopharmacology · 2014Trial
- Lapses of attention.Psychonomic bulletin & review · 2026Review
- Juvenile influenza can impair myelin development and adult behavior through chemokine signaling in mice.bioRxiv : the preprint server for biology · 2026Article
- CGRP reception potentiates anxiety in an influenza A derived immune engram.bioRxiv : the preprint server for biology · 2026Article
- Exploring the association of respiratory infection aetiology with mental well-being scores: a longitudinal study.Frontiers in psychology · 2026Article
- Virtual Reality Gaming and Its Impact and Effectiveness in Improving Eye-Hand Coordination and Attention Concentration in the Oldest-Old Population.Journal of clinical medicine · 2025Article
- Holistic care in mild upper respiratory tract infections (MURTIs): an approach to individualized care management.Drugs in context · 2025Review
- Changes in memory and cognition during the SARS-CoV-2 human challenge study.EClinicalMedicine · 2024Article
- The treatment of mild upper respiratory tract infections - a position paper with recommendations for best practice.Drugs in context · 2023Review
- Upper respiratory tract infections and academic attainment: A case study.Journal of clinical and translational research · 2022Article
- Neurocognitive impact of Zika virus infection in adult rhesus macaques.Journal of neuroinflammation · 2022Article
- Cognitive deficits in people who have recovered from COVID-19.EClinicalMedicine · 2021Article
- Boosting nitric oxide in stress and respiratory infection: Potential relevance for asthma and COVID-19.Brain, behavior, & immunity - health · 2021Review
- Studying the neuropsychological sequelae of SARS-CoV-2: lessons learned from 35 years of neuroHIV research.Journal of neurovirology · 2020Review
- Inflammation Mediates Body Weight and Ageing Effects on Psychomotor Slowing.Scientific reports · 2019Article
- Sulforaphane reduces lipopolysaccharide-induced proinflammatory markers in hippocampus and liver but does not improve sickness behavior.Nutritional neuroscience · 2017Article
- Acute Tension-Type Headaches Are Associated with Impaired Cognitive Function and More Negative Mood.Frontiers in neurology · 2016Article
- Perceived Immune Status and Sleep: A Survey among Dutch Students.Sleep disorders · 2015Article
- The dopamine imbalance hypothesis of fatigue in multiple sclerosis and other neurological disorders.Frontiers in neurology · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Minor illnesses such as the common cold and influenza are frequent and widespread. As well as specific symptoms such as nasal problems and fever, these illnesses are associated with a behavioural malaise. One feature of this malaise is reduced alertness and this has been confirmed using subjective reports and objective measures of performance. Such effects have been obtained with both experimentally induced infections and in studies of naturally occurring illnesses. The mechanisms underlying the effects are unclear but possibly reflect effects of cytokines on the CNS which result in changes in neurotransmitter functioning that lead to reduced alertness. The malaise induced by these illnesses has many real-life consequences and activities such as driving and safety at work may be at risk. These illnesses not only have direct effects on performance and mood but also make the person more sensitive to effects of other negative influences such as noise, alcohol and prolonged work. Countermeasures include ingestion of caffeine and other drugs known to increase alertness.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.