Evidence map›Paper›PMID 23020294›Full record

ReviewAnnual review of pharmacology and toxicology2013

Pharmacology of iron transport.

Shaina L Byrne, Divya Krishnamurthy, Marianne Wessling-Resnick

Abstract readReview
In one paragraph

Review in Annual review of pharmacology and toxicology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Article
  3. Effects of Dietary Ferric EDTA Levels on Vegetables and Mirror Carp (Animals : an open access journal from MDPI · 2025
    Article
  4. Effects of deferoxamine on intrinsic colistin resistance ofExperimental and therapeutic medicine · 2023
    Article
  5. Article
  6. Direct Cell Radiolabeling forChemical reviews · 2022
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. A Radio-Nano-Platform for T1/T2 Dual-Mode PET-MR Imaging.International journal of nanomedicine · 2020
    Article
  12. TACS applied bio materials · 2018
    Article
  13. Article
  14. Iron loading impairs lipoprotein lipase activity and promotes hypertriglyceridemia.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2013
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Shaina L ByrneDepartment of Genetics and Complex Diseases, Harvard School of Public Health, Boston, Massachusetts 02115, USA.
Divya Krishnamurthy
Marianne Wessling-Resnick

Funding

Manganese Transport and ToxicityR01ES014638 · NIEHS · HARVARD SCHOOL OF PUBLIC HEALTH · PI WESSLING-RESNICK, MARIANNE · 2006 to 2017
$4.4M
Microgial Iron Metabolism and Its Regulation by CannabinoidsR01DK064750 · NIDDK · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI LEE, CHIH-HAO · 2004 to 2021
$4.2M
Interdisciplinary Training in Genes and the EnvironmentT32ES016645 · NIEHS · HARVARD SCHOOL OF PUBLIC HEALTH · PI LEE, CHIH-HAO · 2008 to 2018
$4.0M
Ferristatin: A New Small Molecule Inhibitor of Iron TransportRC1DK086774 · NIDDK · HARVARD SCHOOL OF PUBLIC HEALTH · PI WESSLING-RESNICK, MARIANNE · 2009 to 2010
$878k
Cannabinoid Inhibition of Divalent Metal Transporter-1 ActivityR21DA025573 · NIDA · HARVARD SCHOOL OF PUBLIC HEALTH · PI WESSLING-RESNICK, MARIANNE · 2008 to 2009
$449k
HFE: A Genetic Determinant of Olfactory Mn Absorption and ToxicityR03DA027030 · NIDA · HARVARD SCHOOL OF PUBLIC HEALTH · PI WESSLING-RESNICK, MARIANNE · 2009 to 2010
$325k
NIDA NIH HHS R03 DA027030NIDA NIH HHS R21 DA025573NIDDK NIH HHS R01 DK064750NIDDK NIH HHS RC1 DK086774NIEHS NIH HHS R01 ES014638NIEHS NIH HHS T32 ES016645
6 · The paper itself

Abstract

Elucidating the molecular basis for the regulation of iron uptake, storage, and distribution is necessary to understand iron homeostasis. Pharmacological tools are emerging to identify and distinguish among different iron transport pathways. Stimulatory or inhibitory small molecules with effects on iron uptake can help characterize the mechanistic elements of iron transport and the roles of the transporters involved in these processes. In particular, iron chelators can serve as potential pharmacological tools to alleviate diseases of iron overload. This review focuses on the pharmacology of iron transport, introducing iron transport membrane proteins and known inhibitors.

Indexed as

AnimalsBiological TransportHomeostasisHumansIronMembrane ProteinsIronMembrane Proteins

Identifiers

PMID23020294
PMCPMC3837343

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.