Evidence map›Paper›PMID 23019633›Full record

ArticleScience (New York, N.Y.)2012

Response to comment on "the geometric structure of the brain fiber pathways".

Van J Wedeen, Douglas L Rosene, Ruopeng Wang, Guangping Dai, Farzad Mortazavi, Patric Hagmann, Jon H Kaas, Wen-Yih I Tseng

Abstract readComment
In one paragraph

Article in Science (New York, N.Y.), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Van J WedeenDepartment of Radiology, Massachusetts General Hospital, Harvard Medical School and the Martinos Center for Biomedical Imaging, Building 129 13th Street, 2nd floor, Charlestown, MA 02129, USA. van@nmr.mgh.harvard.edu
Douglas L Rosene
Ruopeng Wang
Guangping Dai
Farzad Mortazavi
Patric Hagmann
Jon H Kaas
Wen-Yih I Tseng

Funding

ULTRAHIGH FIELD TECHNOLOGY FOR FUNCTIONAL IMAGINGP41RR014075 · NCRR · MASSACHUSETTS GENERAL HOSPITAL · PI ROSEN, BRUCE R · 1999 to 2011
$16.4M
The Human Connectome Project (HCP)U01MH093765 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI ROSEN, BRUCE R · 2010 to 2014
$12.1M
FUNCTIONAL ORGANIZATION OF THE VISUAL SYSTEMR01EY002686 · NEI · VANDERBILT UNIVERSITY · PI KAAS, JON H · 1985 to 2023
$7.4M
FUNCTIONAL ORGANIZATION OF THE SOMATOSENSORY SYSTEMR01NS016446 · NINDS · VANDERBILT UNIVERSITY · PI KAAS, JON H · 1985 to 2018
$6.9M
TRAINING AND DISSEMINATIONP41RR023953 · NCRR · NORTHERN CALIFORNIA INSTITUTE/RES/EDU · PI WEINER, MICHAEL W · 2008 to 2011
$6.0M
Diffusion MRI of Complex White Matter and ConnectivityR01MH064044 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI SCHMAHMANN, JEREMY D, WEDEEN, VAN J · 2001 to 2013
$5.2M
NCRR NIH HHS P41 RR014075NCRR NIH HHS P41 RR023953NEI NIH HHS R01 EY002686NIMH NIH HHS R01 MH064044NIMH NIH HHS U01 MH093765NINDS NIH HHS R01 NS016446
6 · The paper itself

Abstract

In response to Catani et al., we show that corticospinal pathways adhere via sharp turns to two local grid orientations; that our studies have three times the diffusion resolution of those compared; and that the noted technical concerns, including crossing angles, do not challenge the evidence of mathematically specific geometric structure. Thus, the geometric thesis gives the best account of the available evidence.

Indexed as

Nerve FibersAnimalsCerebral CortexHumansNeural Pathways

Identifiers

PMID23019633
PMCPMC3733383

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.