ArticleAJNR. American journal of neuroradiology2013
Intra-aneurysmal pressure and flow changes induced by flow diverters: relation to aneurysm size and shape.
Article in AJNR. American journal of neuroradiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05526352 (@neurIST), which is not on this map. Cited by 28 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
@neurIST : Informatique biomédicale intégrée Pour la Gestion Des anévrismes cérébraux
Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it, 92 citations in OpenAlex.
- Endothelialization following Flow Diversion for Intracranial Aneurysms: A Systematic Review.AJNR. American journal of neuroradiology · 2019Pooled it
- Treatment outcome of flow-diversion with Surpass Evolve stent for unruptured intracranial aneurysms: Predictors of poor occlusion.Journal of cerebrovascular and endovascular neurosurgery · 2026Article
- The efficacy of intentional compressed placement of flow diverter stent for improvement of operative results against internal carotid artery and posterior communicating artery bifurcation aneurysms: patient series.Journal of neurosurgery. Case lessons · 2025Article
- Hemodynamics in Cerebral Aneurysms and Parent Arteries With Incompletely Expanded Flow Diverter Stents.International journal for numerical methods in biomedical engineering · 2025Article
- Aneurysm dome and vessel pressure measurements with coiling, stent assisted coiling and flow diversion.Acta neurochirurgica · 2025Article
- Letter to the Editor. Coil embolization complications linked to aneurysmal inflammation.Journal of neurosurgery. Case lessons · 2024Article
- Comparison of Flow Reduction Efficacy of Nominal and Oversized Flow Diverters Using a Novel Measurement-assisted in Silico Method.Clinical neuroradiology · 2024Article
- In vitro and in silico assessment of flow modulation after deploying the Contour Neurovascular System in intracranial aneurysm models.Journal of neurointerventional surgery · 2024Article
- Endovascular Treatment of Intracranial Aneurysm: The Importance of the Rheological Model in Blood Flow Simulations.Bioengineering (Basel, Switzerland) · 2024Article
- Effects of different stent wire mesh densities on hemodynamics in aneurysms of different sizes.PloS one · 2022Article
- Role of patient-specific blood properties in computational fluid dynamics simulation of flow diverter deployed cerebral aneurysms.Technology and health care : official journal of the European Society for Engineering and Medicine · 2022Article
- Progressive volume reduction and long-term aneurysmal collapse following flow diversion treatment of giant and symptomatic cerebral aneurysms.Frontiers in neurology · 2022Article
- Hemodynamic Investigation of the Effectiveness of a Two Overlapping Flow Diverter Configuration for Cerebral Aneurysm Treatment.Bioengineering (Basel, Switzerland) · 2021Article
- Intra-saccular device modeling for treatment planning of intracranial aneurysms: from morphology to hemodynamics.International journal of computer assisted radiology and surgery · 2021Article
- Predictors of the Effects of Flow Diversion in Very Large and Giant Aneurysms.AJNR. American journal of neuroradiology · 2021Article
- Cerebral Aneurysm Occlusion at 12-Month Follow-Up After Flow-Diverter Treatment: Statistical Modeling for V&V With Real-World Data.Frontiers in medical technology · 2021Article
- Intracranial Fusiform and Circumferential Aneurysms of the Main Trunk: Therapeutic Dilemmas and Prospects.Frontiers in neurology · 2021Review
- Hydrodynamic Resistance of Intracranial Flow-Diverter Stents: Measurement Description and Data Evaluation.Cardiovascular engineering and technology · 2020Article
- Mechanism of Action and Biology of Flow Diverters in the Treatment of Intracranial Aneurysms.Neurosurgery · 2020Review
- Relationship between haemodynamic changes and outcomes of intracranial aneurysms after implantation of the pipeline embolisation device: a single centre study.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeEffects of blood flow modification by flow diverters are observed to lead often to aneurysm thrombosis and reverse remodeling. For this process, to further understand the potential roles of intra-aneurysmal blood pressure changes and aneurysm morphologies, 23 patients were studied by numeric simulation. MATERIALS AND
methods3D imaging of aneurysms of different sizes and shapes, all located at the supraclinoid segment of the ICA (n=23), was prepared for CFD simulations. Hemodynamic variables were calculated for conditions before and after virtual FD implantation, reconstituting a vessel wall scaffold across the aneurysm neck. WSS, velocity, residence time, turnover time, and intra-aneurysmal pressure were assessed statistically.
resultsAfter placement of FDs, significant reductions inside the aneurysm were observed for most hemodynamic variables (P<.01) except mean intra-aneurysmal pressures. For minimum/maximum intra-aneurysmal pressure values, small but significant changes were found; however, they were considered too small to be of relevance.
conclusionsCalculations in 23 cases did not reveal significant intra-aneurysmal mean or peak pressure changes, indicating a minor role of pressure changes in the rare event of secondary ruptures after FD use. Other hemodynamic variables (WSS and velocity) exhibited more significant changes, indicating their role in intra-aneurysmal thrombus formation. Size-dependent, significantly higher reduction in WSS (P=.069) and velocity (P=.013) was observed in small aneurysms compared with larger ones. When it came to shape, there were significantly higher reductions in WSS (P=.055) and velocity (P=.065) and a significantly higher increase in turnover time in fusiform aneurysms compared with saccular aneurysms.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.