Evidence map›Paper›PMID 23018353›Full record

ArticleMedical science monitor : international medical journal of experimental and clinical research2012

Detecting of breast cancer metastasis by means of regional lymph node sampling during autologous breast reconstruction--a screening of 519 consecutive patients.

Christoph Andree, Volker J Schmidt, Beatrix I J Munder, Katrin Seidenstücker, Philipp Behrendt, Christian Witzel, Raymund E Horch, Brian T Andrews, Philipp Richrath

Open access · hybridAbstract read
In one paragraph

Article in Medical science monitor : international medical journal of experimental and clinical research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Predictive Value of Clinicopathological Characteristics for Sentinel Lymph Node Metastasis in Early Breast Cancer.Medical science monitor : international medical journal of experimental and clinical research · 2017
    Article
  4. Article
  5. Article
  6. Tumor characteristics of breast cancer in predicting axillary lymph node metastasis.Medical science monitor : international medical journal of experimental and clinical research · 2014
    Article
  7. Seasonality pattern of breast, colorectal, and prostate cancer is dependent on latitude.Medical science monitor : international medical journal of experimental and clinical research · 2014
    Article
  8. The clinical significance of lymphangiogenesis in renal cell carcinoma.Medical science monitor : international medical journal of experimental and clinical research · 2013
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Christoph AndreeDepartment of Plastic and Aesthetic Surgery, Interdisciplinary Breast Centre, Sana-Kliniken Düsseldorf, Gerresheim Hospital, Düsseldorf, Germany. christoph.andree@sana.de
Volker J Schmidt
Beatrix I J Munder
Katrin Seidenstücker
Philipp Behrendt
Christian Witzel
Raymund E Horch
Brian T Andrews
Philipp Richrath
Friedrich-Alexander-Universität Erlangen-Nürnberg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe internal mammary artery and vein is often used as a site of anastomoses in microvascular breast reconstruction. This area supports lymphatic drainage of the breast and its role in breast cancer metastasis remains unclear. We hypothesize that sampling of internal mammary lymph nodes at the time of microvascular anastomoses preparation may identify persistent or recurrent local disease and mandate the need for additional treatment in this area. MATERIAL/

methodsA retrospective chart review from 519 patients in the time between January 2006 and September 2009 was performed on all patients who underwent internal mammary lymph node sampling at the time of microvascular breast reconstruction.

resultsMicrovascular breast reconstruction was performed in 519 patients. Enlarged internal mammary lymph nodes were found and harvested in 195 patients for histological review. Six of 195 (3.08%) were found positive for metastatic disease requiring additional oncologic treatment.

conclusionsThe internal mammary lymphatic drainage system is an important and often underappreciated pathway for breast metastasis. Routine sampling of these lymph nodes at the time of microvascular breast reconstruction is easy to perform and is a useful tool to identify women, who might require additional treatment and increase cancer-free survival.

Indexed as

MammaplastySentinel Lymph Node BiopsyAdultAgedBreast NeoplasmsFemaleHumansLymphatic MetastasisLymph NodesMediastinumMiddle AgedNeoadjuvant TherapyTransplantation, AutologousYoung Adult

Identifiers

PMID23018353
PMCPMC3560567
OpenAlexW2005756200

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.