Evidence map›Paper›PMID 23017624›Full record

Trial reportJournal of pain and symptom management2013

A home-based exercise program to improve function, fatigue, and sleep quality in patients with Stage IV lung and colorectal cancer: a randomized controlled trial.

Andrea L Cheville, Jenny Kollasch, Justin Vandenberg, Tiffany Shen, Axel Grothey, Gail Gamble, Jeffrey R Basford

2 registry-linked trialsAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of pain and symptom management, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 134 papers, 27 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
134citing papers in PubMed, 27 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04270500 naunknown statusnot on this mapstarted 2020, after this paper: background citation

The Impact of Physical Exercise on Sleep Quality and Duration in Colorectal Cancer Patients During Prehabilitation Period: A Pilot Study

TypeinterventionalSponsorMontreal General HospitalRan2020 to 2022Enrolled100ConditionsColo-rectal Cancer, SurgeryArmsPrehabilitation program
NCT07234812 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

The Effects of Tailored Resistance Exercise on Sleep Quality in Relation to Chronotype

TypeinterventionalSponsorMedipol UniversityRan2025 to 2026Enrolled64ConditionsPhysical Therapy, Resistance Exercise, Sleep Disturbances, Sleep QualityArmsModerate-Intensity Resistance Exercise Program
3 · Its place in the literature

Who cites it

134 citing papers in PubMed, 27 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Using digital technology to support wellbeing and independence among people living with incurable cancers: a systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Pooled it
  4. Resistance training for fatigue in people with cancer.The Cochrane database of systematic reviews · 2024
    Pooled it
  5. Non-pharmacological interventions targeting mobility among people with advanced cancer: a systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Pooled it
  6. Pooled it
  7. Pooled it
  8. Physical activity and pain in people with cancer: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Pooled it
  9. Pooled it
  10. Pooled it
  11. Guideline
  12. The role of exercise for pain management in adults living with and beyond cancer: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Pooled it
  13. Pooled it
  14. Pooled it
  15. Pooled it
  16. Association between physical activity and patient-reported outcome measures in patients with lung cancer: a systematic review and meta-analysis.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022
    Pooled it
  17. Pooled it
  18. Pooled it
  19. Pooled it
  20. Telephone interventions for symptom management in adults with cancer.The Cochrane database of systematic reviews · 2020
    Pooled it

74 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Andrea L ChevilleDepartment of Physical Medicine and Rehabilitation, Mayo Clinic, Rochester, Minnesota, USA. Cheville.andrea@mayo.edu
Jenny Kollasch
Justin Vandenberg
Tiffany Shen
Axel Grothey
Gail Gamble
Jeffrey R Basford

Funding

Mayo Clinic Center for Translational Science ActivitiesKL2RR024151 · NCRR · MAYO CLINIC ROCHESTER · PI RIZZA, ROBERT A. · 2006 to 2011
$15.3M
NCRR NIH HHS KL2 RR024151NCRR NIH HHS KL2 RR024151-01
6 · The paper itself

Abstract

contextExercise benefits patients with cancer, but studies of home-based approaches, particularly among those with Stage IV disease, remain small and exploratory.

objectivesTo conduct an adequately powered trial of a home-based exercise intervention that can be facilely integrated into established delivery and reimbursement structures.

methodsSixty-six adults with Stage IV lung or colorectal cancer were randomized, in an eight-week trial, to usual care or incremental walking and home-based strength training. The exercising participants were instructed during a single physiotherapy visit and subsequently exercised four days or more per week; training and step-count goals were advanced during bimonthly telephone calls. The primary outcome measure was mobility assessed with the Ambulatory Post Acute Care Basic Mobility Short Form. Secondary outcomes included ratings of pain and sleep quality as well as the ability to perform daily activities (Ambulatory Post Acute Care Daily Activities Short Form), quality of life (Functional Assessment of Cancer Therapy-General), and fatigue (Functional Assessment of Cancer Therapy-Fatigue).

resultsThree participants dropped out and seven died (five in the intervention and two in the control group, P=0.28). At Week 8, the intervention group reported improved mobility (P=0.01), fatigue (P=0.02), and sleep quality (P=0.05) compared with the usual care group, but did not differ on the other measures.

conclusionA home-based exercise program seems capable of improving the mobility, fatigue, and sleep quality of patients with Stage IV lung and colorectal cancer.

Indexed as

Activities of Daily LivingAgedColorectal NeoplasmsExercise TherapyFatigueFemaleHome Care ServicesHumansLiver NeoplasmsMaleMiddle AgedNeoplasm StagingPalliative CareQuality of LifeRecovery of FunctionSleep Wake Disorders

Identifiers

PMID23017624
PMCPMC4524515

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.