Evidence map›Paper›PMID 23017442›Full record

ArticleEmerging infectious diseases2012

Autochthonous and dormant Cryptococcus gattii infections in Europe.

Ferry Hagen, M Francisca Colom, Daniëlle Swinne, Kathrin Tintelnot, Roberta Iatta, Maria Teresa Montagna, Josep M Torres-Rodriguez, Massimo Cogliati, Aristea Velegraki, Arjan Burggraaf and 5 more

Abstract read
In one paragraph

Article in Emerging infectious diseases, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
66citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

66 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. An Emerging Infectious Yeast to Watch:Journal of fungi (Basel, Switzerland) · 2025
    Review
  4. Article
  5. Review
  6. Review
  7. Antifungal Resistance in Cryptococcal Infections.Pathogens (Basel, Switzerland) · 2024
    Review
  8. Article
  9. Article
  10. Article
  11. What's New inJournal of fungi (Basel, Switzerland) · 2022
    Review
  12. Article
  13. Gene, virulence and related regulatory mechanisms inActa biochimica et biophysica Sinica · 2022
    Review
  14. A Possible Link between the Environment andInternational journal of environmental research and public health · 2022
    Article
  15. Article
  16. Article
  17. Medical mycology case reports · 2021
    Article
  18. Review
  19. Article
  20. Article

6 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Ferry HagenRoyal Netherlands Academy of Arts and Sciences Fungal Biodiversity Centre, Utrecht, the Netherlands. f.hagen@gmail.com
M Francisca Colom
Daniëlle Swinne
Kathrin Tintelnot
Roberta Iatta
Maria Teresa Montagna
Josep M Torres-Rodriguez
Massimo Cogliati
Aristea Velegraki
Arjan Burggraaf
Alwin Kamermans
Johanna M Sweere
Jacques F Meis
Corné H W Klaassen
Teun Boekhout

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Until recently, Cryptococcus gattii infections occurred mainly in tropical and subtropical climate zones. However, during the past decade, C. gattii infections in humans and animals in Europe have increased. To determine whether the infections in Europe were acquired from an autochthonous source or associated with travel, we used multilocus sequence typing to compare 100 isolates from Europe (57 from 40 human patients, 22 from the environment, and 21 from animals) with 191 isolates from around the world. Of the 57 human patient isolates, 47 (83%) were obtained since 1995. Among the 40 patients, 24 (60%) probably acquired the C. gattii infection outside Europe; the remaining 16 (40%) probably acquired the infection within Europe. Human patient isolates from Mediterranean Europe clustered into a distinct genotype with animal and environmental isolates. These results indicate that reactivation of dormant C. gattii infections can occur many years after the infectious agent was acquired elsewhere.

Indexed as

AnimalsCommunicable Diseases, EmergingCryptococcosisCryptococcus gattiiEuropeGenotypeHumansMultilocus Sequence TypingPhylogenyTravel

Identifiers

PMID23017442
PMCPMC3471617

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.