ArticleNutrients2012
Vitamin D and calcium status in South African adolescents with alcohol use disorders.
Article in Nutrients, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 47 citations in OpenAlex.
- Association between serum 25-hydroxyvitamin D concentrations and overactive bladder in female: a mediation analysis of inflammatory biomarkers.Frontiers in nutrition · 2026Article
- Factors associated with the serum 25-hydroxyvitamin D levels in adults.BMC nutrition · 2025Article
- Potential roles for vitamin D in preventing and treating impulse control disorders, behavioral addictions, and substance use disorders: A scoping review.Addiction neuroscience · 2025Article
- Alcohol-induced bone loss driven by dysregulated spatial distribution of gut microbiota and PGD2-IL17 pathway-mediated osteoclast activation.Frontiers in microbiology · 2025Article
- Nutritional status of people who inject drugs in Coastal Kenya: a cross-sectional study.BMC nutrition · 2024Article
- Effect of emotion-based nutrition messages on consumption of calcium-rich foods among early adolescents in Ogbomoso, Nigeria.Dialogues in health · 2023Article
- Relationship between serum vitamin D and thyroid hormone profiles in male patients with alcohol dependence.BMC psychiatry · 2023Article
- Association between Vitamin D and Cognitive Deficiency in Alcohol Dependence.Healthcare (Basel, Switzerland) · 2022Article
- Latrophilin-3 disruption: Effects on brain and behavior.Neuroscience and biobehavioral reviews · 2021Review
- Alcohol Use and Abuse Conspires With HIV Infection to Aggravate Intestinal Dysbiosis and Increase Microbial Translocation in People Living With HIV: A Review.Frontiers in immunology · 2021Review
- Provincial Dietary Intake Study (PDIS): Micronutrient Intakes of Children in a Representative/Random Sample of 1- to <10-Year-Old Children in Two Economically Active and Urbanized Provinces in South Africa.International journal of environmental research and public health · 2020Article
- Association Between Serum 25-Hydroxyvitamin D Concentrations and Chronic Pain: Effects of Drinking Habits.Journal of pain research · 2020Article
- Vitamin D and mental health in children and adolescents.European child & adolescent psychiatry · 2017Review
- The relationship between serum vitamin D levels and sleep quality in fixed day indoor field workers in the electronics manufacturing industry in Korea.Annals of occupational and environmental medicine · 2017Article
- Vitamin D Status and Its Consequences for Health in South Africa.International journal of environmental research and public health · 2016Review
- Vitamin D deficiency in adult fracture patients: prevalence and risk factors.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2016Article
- Behavioral and transcriptomic profiling of mice null for Lphn3, a gene implicated in ADHD and addiction.Molecular genetics & genomic medicine · 2016Article
- Cortical bone histomorphology of known-age skeletons from the Kirsten collection, Stellenbosch university, South Africa.American journal of physical anthropology · 2016Article
- Review
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 2 countries.
Funding
Abstract
Adequate vitamin D and calcium are essential for optimal adolescent skeletal development. Adolescent vitamin D insufficiency/deficiency and poor calcium intake have been reported worldwide. Heavy alcohol use impacts negatively on skeletal health, which is concerning since heavy adolescent drinking is a rising public health problem. This study aimed to examine biochemical vitamin D status and dietary intakes of calcium and vitamin D in 12-16 year-old adolescents with alcohol use disorders (AUD), but without co-morbid substance use disorders, compared to adolescents without AUD. Substance use, serum 25-hydroxyvitamin D (s-25(OH)D) concentrations, energy, calcium and vitamin D intakes were assessed in heavy drinkers (meeting DSM-IV criteria for AUD) (n = 81) and in light/non-drinkers without AUD (non-AUD) (n = 81), matched for age, gender, language, socio-economic status and education. Lifetime alcohol dose was orders of magnitude higher in AUD adolescents compared to non-AUD adolescents. AUD adolescents had a binge drinking pattern and "weekends-only" style of alcohol consumption. Significantly lower (p = 0.038) s-25(OH)D (adjusted for gender, smoking, vitamin D intake) were evident in AUD adolescents compared to non-AUD adolescents. High levels of vitamin D insufficiency/deficiency (s-25(OH)D < 29.9 ng/mL) were prevalent in both groups, but was significantly higher (p = 0.013) in the AUD group (90%) compared to the non-AUD group (70%). All participants were at risk of inadequate calcium and vitamin D intakes (Estimated Average Requirement cut-point method). Both groups were at risk of inadequate calcium intake and had poor biochemical vitamin D status, with binge drinking potentially increasing the risk of the latter. This may have negative implications for peak bone mass accrual and future osteoporosis risk, particularly with protracted binge drinking.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.