ArticleSports health2012
Overtraining syndrome: a practical guide.
Article in Sports health, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04059120 (Expression of BNDF Through Stretching as a Recovery Mechanism in Subjects With Overtraining), which is not on this map. Cited by 126 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Expression of BNDF Through Stretching as a Recovery Mechanism in Subjects With Overtraining
Who cites it
126 citing papers in PubMed, 5 syntheses or guidelines pooled it, 340 citations in OpenAlex.
- Effect of flywheel resistance training on change of direction performance in team sports: A systematic review and meta-analysis.Medicine · 2026Pooled it
- Optimal exercise modality and dose for alleviating depressive symptoms in postmenopausal women: a systematic review and network meta-analysis of randomized controlled trials.Frontiers in psychology · 2025Pooled it
- Impact of Overtraining on Cognitive Function in Endurance Athletes: A Systematic Review.Sports medicine - open · 2023Pooled it
- Effect of core training on athletic and skill performance of basketball players: A systematic review.PloS one · 2023Pooled it
- External and Internal Load Variables Encountered During Training and Games in Female Basketball Players According to Playing Level and Playing Position: A Systematic Review.Sports medicine - open · 2022Pooled it
- The effects of physical activity on mental health in adolescents with attention-deficit hyperactivity disorder: a randomized controlled trial.The international journal of behavioral nutrition and physical activity · 2025Trial
- Ketone ester supplementation blunts overreaching symptoms during endurance training overload.The Journal of physiology · 2019Trial
- The Impact of Overtraining on Anxiety-Like Behavior and Tight Junction Proteins of the Blood-Brain Barrier in Mice.Brain and behavior · 2026Article
- Comparative and Dose-Response Effects of Exercise Modalities on Sleep Quality in Individuals With Breast Cancer: A Bayesian Network Meta-Analysis.Psycho-oncology · 2026Article
- Gene-Physical Activity Interplay in Depression: Candidate-Gene Interactions, Polygenic Susceptibility, Lifestyle Context, and Mendelian Randomization Evidence-Systematic Review.Journal of clinical medicine · 2026Review
- Optimizing Athletic Performance: A Systems Framework for Adaptive Training, Load Management, and Decision-Making.Journal of functional morphology and kinesiology · 2026Review
- Unpacking the Ethiopian paradox of career durability in elite endurance runners via a mixed methods study.Discover mental health · 2026Article
- Pulse Rate Variability Is Not the Same as Heart Rate Variability: Implications for Sports Performance and Injury Prevention.Sports medicine - open · 2026Article
- Probiotics and the Gut Microbiome in Combat Sports: A Narrative Review of Performance, Recovery, and Health Pathways.Probiotics and antimicrobial proteins · 2026Review
- Review
- Temporal Metabolomics Profiling Reveals Liver Metabolic Control in Single and Repeated Exhaustive Exercise in Murine Models.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026Article
- Relieving or Aggravating? The Longitudinal Moderating Role of Challenge and Hindrance Academic Stressors on the Relationship Between Leisure-Time Physical Activity and Context-Specific Anxiety Symptoms Among University Faculty.Behavioral sciences (Basel, Switzerland) · 2026Article
- Biomarkers as Temporal Signals: A Decision-Linked Multi-Layer Framework for Exercise Recovery, Overload, and Adaptation.International journal of molecular sciences · 2026Review
- Molecular Biomarkers of Training Responses: A Systems Framework for Exercise Adaptation and Athlete Monitoring.International journal of molecular sciences · 2026Review
- Physical Activity, Metabolic Risk and the Primary Allostatic Load Mediators: An Explorative Study.Sports (Basel, Switzerland) · 2026Article
66 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
contextFatigue and underperformance are common in athletes. Understanding overtraining syndrome (OTS) is helpful in the evaluation, management, and education of athletes. EVIDENCE ACQUISITION: Relevant articles in English were searched with OVID (1948-2011) and PubMed using the following keywords: overtraining syndrome, overtraining, overreaching, unexplained underperformance, staleness, pathophysiology, management, treatment, evaluation. Bibliographies were reviewed for additional resources.
resultsOTS appears to be a maladapted response to excessive exercise without adequate rest, resulting in perturbations of multiple body systems (neurologic, endocrinologic, immunologic) coupled with mood changes. Many hypotheses of OTS pathogenesis are reviewed, and a clinical approach to athletes with possible OTS (including history, testing, and prevention) is presented.
conclusionsOTS remains a clinical diagnosis with arbitrary definitions per the European College of Sports Science's position statement. History and, in most situations, limited serologies are helpful. However, much remains to be learned given that most past research has been on athletes with overreaching rather than OTS.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.