Evidence map›Paper›PMID 23015517›Full record

ArticleJournal of laboratory automation2012

Cellular-level surgery using nano robots.

Bo Song, Ruiguo Yang, Ning Xi, Kevin Charles Patterson, Chengeng Qu, King Wai Chiu Lai

Abstract read
In one paragraph

Article in Journal of laboratory automation, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Advanced tools and methods for single-cell surgery.Microsystems & nanoengineering · 2022
    Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Bo SongDepartment of Electrical and Computer Engineering, Michigan State University, East Lansing, Michigan 48824, USA.
Ruiguo Yang
Ning Xi
Kevin Charles Patterson
Chengeng Qu
King Wai Chiu Lai

Funding

Novel single cell disease markers with a hybrid AFM scanning piezo-thermal probeR43GM084520 · NIGMS · KYTARO, INC. · PI GAITAS, ANGELO · 2008 to 2009
$400k
NIGMS NIH HHS R43 GM084520
6 · The paper itself

Abstract

The atomic force microscope (AFM) is a popular instrument for studying the nano world. AFM is naturally suitable for imaging living samples and measuring mechanical properties. In this article, we propose a new concept of an AFM-based nano robot that can be applied for cellular-level surgery on living samples. The nano robot has multiple functions of imaging, manipulation, characterizing mechanical properties, and tracking. In addition, the technique of tip functionalization allows the nano robot the ability for precisely delivering a drug locally. Therefore, the nano robot can be used for conducting complicated nano surgery on living samples, such as cells and bacteria. Moreover, to provide a user-friendly interface, the software in this nano robot provides a "videolized" visual feedback for monitoring the dynamic changes on the sample surface. Both the operation of nano surgery and observation of the surgery results can be simultaneously achieved. This nano robot can be easily integrated with extra modules that have the potential applications of characterizing other properties of samples such as local conductance and capacitance.

Indexed as

Automation, LaboratoryCytological TechniquesMicroscopy, Atomic ForceNanotechnologyRobotics

Identifiers

PMID23015517
PMCPMC4190063

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.