Evidence map›Paper›PMID 23015490›Full record

ReviewMethods in molecular biology (Clifton, N.J.)2012

The Helicobacter pylori cag Pathogenicity Island.

Jennifer M Noto, Richard M Peek

Abstract readReview
In one paragraph

Review in Methods in molecular biology (Clifton, N.J.), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 1 pooled it
57.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 1 synthesis or guideline pooled it, 90 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Frontiers in microbiology · 2025
    Article
  6. Microorganisms · 2024
    Review
  7. Article
  8. Article
  9. Review
  10. Biomedical reports · 2023
    Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. The Microbiome in Gastrointestinal Cancers.Gastroenterology clinics of North America · 2022
    Review
  17. Article
  18. Helicobacter pylori: an up-to-date overview on the virulence and pathogenesis mechanisms.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2022
    Review
  19. TheInternational journal of molecular sciences · 2022
    Article
  20. Infection and drug resistance · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Jennifer M NotoDivision of Gastroenterology, Department of Medicine, Vanderbilt University Medical Center, MRB IV 1030C MRB IV, Nashville, TN, USA. jennifer.noto@vanderbilt.edu
Richard M Peek
Vanderbilt University Medical Center · US

Funding

Translational Analysis CoreP30DK058404 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RICHARD M. PEEK · 2002 to 2026
$29.9M
Role of Iron and B-Catenin Activation in Gastric CarcinogenesisP01CA116087 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RICHARD M. PEEK · 2009 to 2026
$27.5M
H.Pylori Relationship to Digestive Diseases and CancerR01CA077955 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RICHARD M. PEEK · 2003 to 2026
$9.7M
Helicobacter Pylori and Gastrointestinal BiologyR01DK058587 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI PEEK, RICHARD M. · 2001 to 2024
$7.8M
Mechanism that regulate Helicobacter pylori-induced beta-caterin activationR01DK073902 · NIDDK · VANDERBILT UNIVERSITY · PI PEEK, RICHARD M. · 2006 to 2009
$1.2M
NCI NIH HHS P01 CA116087NCI NIH HHS R01 CA077955NIDDK NIH HHS P30 DK058404NIDDK NIH HHS R01 DK058587NIDDK NIH HHS R01 DK073902
6 · The paper itself

Abstract

The cag pathogenicity island is a well-characterized virulence determinant. It is composed of 32 genes that encode a type IV bacterial secretion system and is linked with a more severe clinical outcome. The following chapters will explore the manipulation of bacterial factors in order to understand their role in gastric mucosal disease.

Indexed as

Genomic IslandsAntigens, BacterialBacterial ProteinsHelicobacter pyloriHumansPeptidoglycanPhosphorylationSignal TransductionAntigens, BacterialBacterial ProteinscagA protein, Helicobacter pyloriPeptidoglycan

Identifiers

PMID23015490
PMCPMC3547679
OpenAlexW1554191723

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.