ReviewNMR in biomedicine2013
Strategies for the development of gadolinium-based 'q'-activatable MRI contrast agents.
Review in NMR in biomedicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 24 citations in OpenAlex.
- Mapping light distribution in tissue by using MRI-detectable photosensitive liposomes.Nature biomedical engineering · 2023Article
- Synthesis and Comparative Evaluation of Photoswitchable Magnetic Resonance Imaging Contrast Agents.ACS omega · 2020Article
- Hydration number: crucial role in nuclear magnetic relaxivity of Gd(III) chelate-based nanoparticles.Scientific reports · 2017Article
- Activatable interpolymer complex-superparamagnetic iron oxide nanoparticles as magnetic resonance contrast agents sensitive to oxidative stress.Colloids and surfaces. B, Biointerfaces · 2017Article
- Advances in Monitoring Cell-Based Therapies with Magnetic Resonance Imaging: Future Perspectives.International journal of molecular sciences · 2017Review
- Aqueous Lanthanide Chemistry in Asymmetric Catalysis and Magnetic Resonance Imaging.Synlett : accounts and rapid communications in synthetic organic chemistry · 2016Article
- Molecular Magnetic Resonance Imaging of Tumor Response to Therapy.Scientific reports · 2015Article
- Basic MR relaxation mechanisms and contrast agent design.Journal of magnetic resonance imaging : JMRI · 2015Review
- Overcoming the concentration-dependence of responsive probes for magnetic resonance imaging.Metallomics : integrated biometal science · 2015Review
- pH-Sensitive MR Responses Induced by Dendron-Functionalized SPIONs.The journal of physical chemistry. C, Nanomaterials and interfaces · 2013Article
- Overhauser-enhanced MRI of elastase activity from in vitro human neutrophil degranulation.PloS one · 2013Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
The emergence and rapid development of activatable contrast agents (CAs), whose relaxivity changes in response to the variation of a specific marker in the surrounding physiological microenvironment, have expanded the scope of MRI beyond anatomical and functional imaging to also convey information at the cellular and molecular level. The essence of an activatable MRI CA is the difference in relaxivity before and after a change in a physiological variable: the larger the difference, the better the CA. In this review, strategies for the design of activatable gadolinium CAs, with a switching mechanism based on the modulation of hydration (q), sensitive to common variables in the physiological microenvironment, such as pH, light, redox and metal ions, are illustrated and discussed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.