Evidence map›Paper›PMID 23014976›Full record

ArticleInternational journal of colorectal disease2013

i-Scan high-definition white light endoscopy and colorectal polyps: prediction of histology, interobserver and intraobserver agreement.

Flavia Pigò, Helga Bertani, Mauro Manno, Vincenzo Mirante, Angelo Caruso, Carmelo Barbera, Raffaele Manta, Gabrio Bassotti, Gianpiero Olivetti, Rita Luisa Conigliaro

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Article in International journal of colorectal disease, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Image enhanced colonoscopy: updates and prospects-a review.Translational gastroenterology and hepatology · 2023
    Review
  4. Review
  5. Article
  6. Review
  7. Optical Diagnosis of Colorectal Polyps: Recent Developments.Current treatment options in gastroenterology · 2019
    Review
  8. Article
  9. Article
  10. Can technology increase adenoma detection rate?Therapeutic advances in gastroenterology · 2018
    Review
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Flavia PigòDigestive Endoscopy Unit, New Civil Hospital S. Agostino Estense of Modena, Modena, Italy. flaviapigo@virgilio.it
Helga Bertani
Mauro Manno
Vincenzo Mirante
Angelo Caruso
Carmelo Barbera
Raffaele Manta
Gabrio Bassotti
Gianpiero Olivetti
Rita Luisa Conigliaro

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAim of the study was the evaluation of high-definition white light (HDWL) i-Scan endoscopy for diagnostic prediction of histology, inter- and intraobserver agreement for colorectal polyps.

methodsIn this prospective single-center cohort study, a skilled endoscopist, with HDWL i-Scan, predicted on real-time the histology of 150 polyps from 78 patients undergoing colonoscopy. Subsequently, four endoscopists, not involved in the collection of cases, predicted the polyps' histology (neoplastic vs nonneoplastic) and repeated the assessment after 6 months.

resultsReal-time assessment of the lesions predicted a correct histology in 138/150 cases with a sensitivity, specificity, and accuracy of 95, 82, and 92 %, respectively. Sensitivity, specificity, and accuracy of post-acquisition evaluation were 87.7, 61.7, and 82.2 %, respectively. The κ values of inter- and intraobserver agreement of prediction of histology were 0.462 (0.373-0.537) and 0.657 (0.523-0.917). Among the subset of polyps (n = 82) with good/excellent quality image, sensitivity and accuracy of HDWL i-Scan improved (97 %, p = 0.003 and 94 %, p = 0.002, respectively) as well as κ value of interobserver agreement (0.699).

conclusionsHDWL i-Scan technology helps for characterization of polyps of the colon with good accuracy even if it cannot replace, at the moment, the histopathological examination. Reproducibility among operators is supported by a moderate substantial interobserver and intraobserver agreement.

Indexed as

LightColonic PolypsColonoscopyFemaleHumansItalyMaleMiddle AgedObserver VariationSensitivity and Specificity

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.