ArticleAmerican journal of human genetics1990
The power of identity-by-state methods for linkage analysis.
Article in American journal of human genetics, 1990. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
39 citing papers in PubMed, 147 citations in OpenAlex.
- Private detection of relatives in forensic genomics using homomorphic encryption.BMC medical genomics · 2024Article
- Two-locus identity coefficients in pedigrees.G3 (Bethesda, Md.) · 2023Article
- Identification and validation of a key genomic region on chromosome 6 for resistance to Fusarium stalk rot in tropical maize.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2022Article
- Applications and Challenges of Machine Learning Methods in Alzheimer's Disease Multi-Source Data Analysis.Current genomics · 2021Review
- Identification and Validation of Genomic Regions Associated With Charcoal Rot Resistance in Tropical Maize by Genome-Wide Association and Linkage Mapping.Frontiers in plant science · 2021Article
- Genome-wide association studies in tropical maize germplasm reveal novel and known genomic regions for resistance to Northern corn leaf blight.Scientific reports · 2020Article
- Identification and validation of genomic regions influencing kernel zinc and iron in maize.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2018Article
- Genome-wide association study in Asia-adapted tropical maize reveals novel and explored genomic regions for sorghum downy mildew resistance.Scientific reports · 2018Article
- An Object-Oriented Regression for Building Disease Predictive Models with Multiallelic HLA Genes.Genetic epidemiology · 2016Article
- Fine mapping of Msv1, a major QTL for resistance to Maize Streak Virus leads to development of production markers for breeding pipelines.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2015Article
- Posterior predictive checks to quantify lack-of-fit in admixture models of latent population structure.Proceedings of the National Academy of Sciences of the United States of America · 2015Article
- Genome-wide association analysis reveals new targets for carotenoid biofortification in maize.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2015Article
- Estimating heritability of complex traits from genome-wide association studies using IBS-based Haseman-Elston regression.Frontiers in genetics · 2014Article
- Current gene discovery strategies for ocular conditions.Investigative ophthalmology & visual science · 2011Review
- Inference of relationships in population data using identity-by-descent and identity-by-state.PLoS genetics · 2011Article
- Visualization of shared genomic regions and meiotic recombination in high-density SNP data.PloS one · 2009Article
- Unraveling a multifactorial late-onset disease: from genetic susceptibility to disease mechanisms for age-related macular degeneration.Annual review of genomics and human genetics · 2009Review
- The genetics of tobacco use: methods, findings and policy implications.Tobacco control · 2002Article
- Defining the genetic contribution of type 2 diabetes mellitus.Journal of medical genetics · 2001Review
- Statistical tests for detection of misspecified relationships by use of genome-screen data.American journal of human genetics · 2000Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
The affected-sib-pair method has been widely utilized for mapping. This methodology is aimed at mapping complex traits which have been observed to be familial but for which Mendelian segregation, even after allowing for partial penetrance, is not apparent. Indications of linkage are based on the observation of nonrandom segregation at a marker locus in two affected siblings. We extend this methodology to more distant genetic relationships and examine the power of identity-by-state methods for mapping when marker information is only available on pairs of affected relatives. The power depends on the polymorphism of the marker, the probability of identity by descent at the trait locus, and the recombination fraction between the trait and the marker loci.
Indexed as
Identifiers
2301395PMC1684982W1484562168What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.