ReviewThe Yale journal of biology and medicine2012
The role of circadian clocks in metabolic disease.
Review in The Yale journal of biology and medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 47 citations in OpenAlex.
- Late-afternoon endurance exercise is more effective than morning endurance exercise at improving 24-h glucose and blood lipid levels.Frontiers in endocrinology · 2022Trial
- Diet-induced obesity dampens the temporal oscillation of hepatic mitochondrial lipids.Journal of lipid research · 2025Article
- Circadian Regulation of Lipid Metabolism during Pregnancy.International journal of molecular sciences · 2024Review
- Circadian Syndrome Is Associated with Dietary Patterns among Middle-Older Americans: The Health and Retirement Study.Nutrients · 2024Article
- Nrf2 modulates the benefits of evening exercise in type 2 diabetes.Sports medicine and health science · 2023Review
- Gut microbes and the liver circadian clock partition glucose and lipid metabolism.The Journal of clinical investigation · 2023Article
- Chrono-exercise: Time-of-day-dependent physiological responses to exercise.Sports medicine and health science · 2023Review
- Implication of DNA methylation during lifestyle mediated weight loss.Frontiers in endocrinology · 2023Review
- Circadian rhythms-related disorders in diurnal fat sand rats under modern lifestyle conditions: A review.Frontiers in physiology · 2022Review
- Circadian Regulation and Clock-Controlled Mechanisms of Glycerophospholipid Metabolism from Neuronal Cells and Tissues to Fibroblasts.Molecular neurobiology · 2022Review
- Only time will tell: the interplay between circadian clock and metabolism.Chronobiology international · 2021Review
- Linking type 2 diabetes mellitus, cardiac hypertrophy and depression in a diurnal animal model.Scientific reports · 2019Article
- The Circadian Syndrome: is the Metabolic Syndrome and much more!Journal of internal medicine · 2019Review
- Calorie restriction reprograms diurnal rhythms in protein translation to regulate metabolism.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2019Article
- Circadian dysrhythmia-linked diabetes mellitus: Examining melatonin's roles in prophylaxis and management.World journal of diabetes · 2018Review
- Circadian regulation of glucose, lipid, and energy metabolism in humans.Metabolism: clinical and experimental · 2018Review
- Modeling the Influence of Seasonal Differences in the HPA Axis on Synchronization of the Circadian Clock and Cell Cycle.Endocrinology · 2018Article
- Convergence of hepcidin deficiency, systemic iron overloading, heme accumulation, and REV-ERBα/β activation in aryl hydrocarbon receptor-elicited hepatotoxicity.Toxicology and applied pharmacology · 2017Article
- Article
- Crosstalk between circadian rhythmicity, mitochondrial dynamics and macrophage bactericidal activity.Immunology · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The circadian clock is a highly conserved timing system, resonating physiological processes to 24-hour environmental cycles. Circadian misalignment is emerging as a risk factor of metabolic disease. The molecular clock resides in all metabolic tissues, the dysfunction of which is associated with perturbed energy metabolism. In this article, we will review current knowledge about molecular mechanisms of the circadian clock and the role of clocks in the physiology and pathophysiology of metabolic tissues.
Indexed as
Identifiers
23012586PMC3447202W1573412279What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.