ArticleThe Plant cell2012
YSL16 is a phloem-localized transporter of the copper-nicotianamine complex that is responsible for copper distribution in rice.
Article in The Plant cell, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers.
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64 citing papers in PubMed, 197 citations in OpenAlex.
- Seasonal Variation in Leaf Mineral Nutrients and the Determination of the Nutritional Diagnostic Period ofPlants (Basel, Switzerland) · 2026Article
- Functional characterization of transporter genes in rice node at single-cell resolution through multi-omics technologies.Genome biology · 2026Article
- Emerging Mechanisms of Plant Responses to Abiotic Stress.Plants (Basel, Switzerland) · 2025Review
- Barriers and carriers for transition metal homeostasis in plants.Plant communications · 2025Review
- Copper connections: coordinating transport, sensing and systemic signalling in plants.Quantitative plant biology · 2025Review
- Biofortification of Triticum species: a stepping stone to combat malnutrition.BMC plant biology · 2024Review
- Molecular Mechanisms of Plant Responses to Copper: From Deficiency to Excess.International journal of molecular sciences · 2024Review
- Decrypting Molecular Mechanisms Involved in Counteracting Copper and Nickel Toxicity in Jack Pine (Plants (Basel, Switzerland) · 2024Article
- Article
- Nicotianamine: A Key Player in Metal Homeostasis and Hyperaccumulation in Plants.International journal of molecular sciences · 2023Review
- Physiological and Molecular Mechanisms of Plant Responses to Copper Stress.International journal of molecular sciences · 2022Review
- Synergistic Interaction between Copper and Nitrogen-Uptake, Translocation, and Distribution in Rice Plant.Plants (Basel, Switzerland) · 2022Article
- The key micronutrient copper orchestrates broad-spectrum virus resistance in rice.Science advances · 2022Article
- Strategies and Bottlenecks in Hexaploid Wheat to Mobilize Soil Iron to Grains.Frontiers in plant science · 2022Review
- Genome-Wide Identification and Transcript Analysis Reveal Potential Roles of Oligopeptide Transporter Genes in Iron Deficiency Induced Cadmium Accumulation in Peanut.Frontiers in plant science · 2022Article
- Article
- Low-molecular-weight ligands in plants: role in metal homeostasis and hyperaccumulation.Photosynthesis research · 2021Review
- Adaptive Responses ofInternational journal of molecular sciences · 2021Article
- Transcriptome Profiling of Cu Stressed Petunia Petals Reveals Candidate Genes Involved in Fe and Cu Crosstalk.International journal of molecular sciences · 2021Article
- Overexpression of OsLCT2, a Low-Affinity Cation Transporter Gene, Reduces Cadmium Accumulation in Shoots and Grains of Rice.Rice (New York, N.Y.) · 2021Article
4 more citing papers are in PubMed but not listed here.
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4 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Cu is an essential element for plant growth, but the molecular mechanisms of its distribution and redistribution within the plants are unknown. Here, we report that Yellow stripe-like16 (YSL16) is involved in Cu distribution and redistribution in rice (Oryza sativa). Rice YSL16 was expressed in the roots, leaves, and unelongated nodes at the vegetative growth stage and highly expressed in the upper nodes at the reproductive stage. YSL16 was expressed at the phloem of nodes and vascular tissues of leaves. Knockout of this gene resulted in a higher Cu concentration in the older leaves but a lower concentration in the younger leaves at the vegetative stage. At the reproductive stage, a higher Cu concentration was found in the flag leaf and husk, but less Cu was present in the brown rice, resulting in a significant reduction in fertility in the knockout line. Isotope labeling experiments with (65)Cu showed that the mutant lost the ability to transport Cu-nicotianamine from older to younger leaves and from the flag leaf to the panicle. Rice YSL16 transported the Cu-nicotianamine complex in yeast. Taken together, our results indicate that Os-YSL16 is a Cu-nicotianamine transporter that is required for delivering Cu to the developing young tissues and seeds through phloem transport.
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