ReviewCurrent allergy and asthma reports2012
Otitis media in infancy and the development of asthma and atopic disease.
Review in Current allergy and asthma reports, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 24 citations in OpenAlex.
- Early childhood respiratory tract infections according to parental subfertility and conception by assisted reproductive technologies.Human reproduction (Oxford, England) · 2022Article
- The Role of Allergen-Specific Immunotherapy in ENT Diseases: A Systematic Review.Journal of personalized medicine · 2022Review
- IL-17 is a Potential Therapeutic Target in a Rodent Model of Otitis Media with Effusion.Journal of inflammation research · 2022Article
- Bidirectional association between asthma and otitis media in children.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2021Article
- Allergy and Otitis Media in Clinical Practice.Current allergy and asthma reports · 2020Review
- Altered Middle Ear Microbiome in Children With Chronic Otitis Media With Effusion and Respiratory Illnesses.Frontiers in cellular and infection microbiology · 2019Article
- The Influence of Age on the Relationship Between Allergic Rhinitis and Otitis Media.Current allergy and asthma reports · 2018Review
- Role of Inflammatory Risk Factors in the Pathogenesis ofFrontiers in immunology · 2018Review
- Risks for comorbidity in children with atopic disorders: an observational study in Dutch general practices.BMJ open · 2017Observational
- Otitis media with effusion and atopy: is there a causal relationship?The World Allergy Organization journal · 2017Review
- Update on otitis media - prevention and treatment.Infection and drug resistance · 2014Review
- Mining and Visualizing Family History Associations in the Electronic Health Record: A Case Study for Pediatric Asthma.AMIA ... Annual Symposium proceedings. AMIA SymposiumArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Otitis media is a frequent respiratory infection of early childhood and it is important to fully understand the long-term complications and sequelae. Literature examining otitis media in early childhood and subsequent development of atopic disease is sparse despite there being vast literature on the association between respiratory infections and atopic disease. Current data support the hypothesis that otitis media infections in early life, especially frequent or severe infections, influence the developing immune system, resulting in increased risk for asthma. Recent findings have also reported an association between otitis media and eczema. Atopic children and those with a family history of atopy appear to be at greater risk. Future work should investigate the specific mechanisms involved. It is possible that vaccines and preventive strategies aimed at reducing the burden of otitis media could also reduce the burden of childhood asthma and atopic disease.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.